Browsing Research Publications and Outputs by author "Aitken, Jade B."
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High mitochondrial accumulation of new gadolinium(III) agents within tumour cells
Morrison, Daniel E.; Aitken, Jade B.; de Jonge, Martin D.; Ioppolo, Joseph A.; Harris, Hugh H.; Rendina, Louis M.Published 2014-01-01The first bifunctional Gd(III) complexes covalently bound to arylphosphonium cations and the first tumour-cell selective mitochondrial agents designed for potential application in binary cancer therapies are reported. The ...Open AccessArticle -
Synchrotron X-ray fluorescence studies of a bromine-labelled cyclic RGD peptide interacting with individual tumor cells
Sheridan, Erin J.; Austin, Christopher J. D.; Aitken, Jade B.; Vogt, Stefan; Jolliffe, Katrina A.; Harris, Hugh H.; Rendina, Louis M.Published 2013-01-01The first example of synchrotron X-ray fluorescence imaging of cultured mammalian cells in cyclic peptide research is reported. The study reports the first quantitative analysis of the incorporation of a bromine-labelled ...Open AccessArticle -
Synthesis and biological evaluation of a class of mitochondrially-targeted gadolinium(III) agents
Morrison, Daniel E.; Aitken, Jade B.; de Jonge, Martin D.; Issa, Fatiah; Harris, Hugh H.; Rendina, Louis M.Published 2014-10-16A structure–activity relationship study of a library of novel bifunctional GdIII complexes covalently linked to arylphosphonium cations is reported. Such complexes have been designed for potential application in binary ...Open AccessArticle
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