Synchrotron X-ray fluorescence studies of a bromine-labelled cyclic RGD peptide interacting with individual tumor cells
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Open Access
Type
ArticleAuthor/s
Sheridan, Erin J.Austin, Christopher J. D.
Aitken, Jade B.
Vogt, Stefan
Jolliffe, Katrina A.
Harris, Hugh H.
Rendina, Louis M.
Abstract
The first example of synchrotron X-ray fluorescence imaging of cultured mammalian cells in cyclic peptide research is reported. The study reports the first quantitative analysis of the incorporation of a bromine-labelled cyclic RGD peptide and its effects on the biodistribution of endogenous elements (for example, K and Cl) within individual tumor cells.The first example of synchrotron X-ray fluorescence imaging of cultured mammalian cells in cyclic peptide research is reported. The study reports the first quantitative analysis of the incorporation of a bromine-labelled cyclic RGD peptide and its effects on the biodistribution of endogenous elements (for example, K and Cl) within individual tumor cells.
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Date
2013-01-01Publisher
Wiley-BlackwellLicence
OtherFaculty/School
Faculty of Science, School of ChemistryCitation
J. Synchrotron Rad. (2013). 20, 226-233Share