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  • Syntheses and reductions of C-dimesitylboryl-1,2-dicarba-closo-dodecaboranes 

    Kahlert, Jan; Böhling, Lena; Brockhinke, Andreas; Stammler, Hans-Georg; Neumann, Beate; Rendina, Louis M.; Low, Paul J.; Weber, Lothar; Fox, Mark A.
    Published 2015-04-24
    Two C-dimesitylboryl-1,2-dicarba-closo-dodecaboranes, 1-(BMes2)-2-R-1,2-C2B10H10 (1, R = H, 2, R = Ph), were synthesised by lithiation of 1,2-dicarba-closo-dodecaborane and 1-phenyl-1,2-dicarba-closo-dodecaborane, respectively, ...
    Open Access
    Article
  • The first indoleamine-2,3-dioxygenase-1 (IDO1) inhibitors containing carborane 

    Austin, Christopher J. D.; Kahlert, Jan; Issa, Fatiah; Reed, John H.; Smith, Jason R.; Ioppolo, Joseph A.; Ong, Jennifer A.; Jamie, Joanne F.; Hibbs, David; Rendina, Louis M.
    Published 2014-04-22
    Indoleamine-2,3-dioxygenase-1 (IDO1) is a critical immunoregulatory enzyme responsible for the metabolism of tryptophan during inflammation and disease. Based upon a pyranonaphthoquinone framework, the first examples of ...
    Open Access
    Article
  • Efficient radiosynthesis of a [18F]-phosphonium salt containing closo-carborane 

    Ioppolo, Joseph A.; Giboureau, Nicolas; Bhadbhade, Mohan; Morrison, Daniel E.; Kassiou, Michael; Rendina, Louis M.
    Published 2017-11-15
    An efficient synthesis of an 18F-labelled phosphonium salt containing closo-carborane is described. The preparation of this salt was attempted using both single-step and two-step protocols, with greater success found for ...
    Open Access
    Article
  • Site-specific synthesis of a hybrid boron-graphene salt 

    Kahlert, Jan U.; Austin, Christopher J. D.; Hall, Andrew J.; Rawal, Aditya; Hook, James M.; Rendina, Louis M.; Choucair, Mohammad
    Published 2016-01-01
    We report the first example of an ionic graphene salt containing boron. An anionic charge is introduced to the graphene surface by means of 7,8-nido-[C2B9H11]− carborane clusters covalently and electronically bound to the ...
    Open Access
    Article
  • Tumor cell uptake and selectivity of gadolinium(III)-phosphonium complexes: The role of delocalisation at the phosphonium centre 

    Busse, Madleen; Windsor, Madeline S. A.; Tefay, Alexander J.; Kardashinsky, Mingyue; Fenton, Jacob M.; Morrison, Daniel E.; Harris, Hugh H.; Rendina, Louis M.
    Published 2017-12-01
    The synthesis of a series of bifunctional Gd(III) complexes 1–3 covalently bound to arylphosphonium cations possessing a varying degree of delocalisation at the phosphonium centre is presented. The influence of the degree ...
    Open Access
    Article

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