Stimuli-responsive cycloaurated ‘OFF-ON’ switchable anion transporters
| Field | Value | Language |
| dc.contributor.author | Fares, Mohamed | |
| dc.contributor.author | Wu, Xin | |
| dc.contributor.author | Ramesh, Deepthi | |
| dc.contributor.author | Lewis, William | |
| dc.contributor.author | Keller, Paul A. | |
| dc.contributor.author | Howe, Ethan N.W. | |
| dc.contributor.author | Pérez-Tomás, Ricardo | |
| dc.contributor.author | Gale, Philip A. | |
| dc.date.accessioned | 2020-10-26 | |
| dc.date.available | 2020-10-26 | |
| dc.date.issued | 2020-01-01 | en_AU |
| dc.identifier.uri | https://hdl.handle.net/2123/23683 | |
| dc.description.abstract | Anion transporters have shown potential application as anti-cancer agents that function by disrupting homeostasis and triggering cell death. In this research article we report switchable anion transport by gold complexes of anion transporters that are ‘switched on’ in situ in the presence of the reducing agent GSH by decomplexation of gold. GSH is found in higher concentrations in tumours than in healthy tissue and hence this approach offers a strategy to target these systems to tumours. | en_AU |
| dc.language.iso | en | en_AU |
| dc.publisher | Wiley-VCH GmbH | en_AU |
| dc.relation.ispartof | Angewandte Chemie International Edition | en_AU |
| dc.rights | Copyright All Rights Reserved | en_AU |
| dc.subject | anion transport · gold complexes · molecular switch · reduction kinetics · supramolecular chemistry | en_AU |
| dc.title | Stimuli-responsive cycloaurated ‘OFF-ON’ switchable anion transporters | en_AU |
| dc.type | Article | en_AU |
| dc.subject.asrc | 0303 Macromolecular and Materials Chemistry | en_AU |
| dc.identifier.doi | 10.1002/anie.202006392 | |
| dc.relation.arc | DP200100453 | |
| dc.rights.other | "This is the peer reviewed version of the following articleM. Fares, X. Wu, D. Ramesh, W. Lewis, P. A. Keller, E. N. W. Howe, R. Pérez-Tomás, P. A. Gale, Angew. Chem. Int. Ed. 2020, 59, 17614,,which has been published in final form at https://doi.org/10.1002/anie.202006392.This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. | en_AU |
| usyd.faculty | SeS faculties schools::Faculty of Science::School of Chemistry | en_AU |
| usyd.citation.volume | 59 | en_AU |
| usyd.citation.spage | 17614 | en_AU |
| usyd.citation.epage | 17621 | en_AU |
| workflow.metadata.only | No | en_AU |
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