Molecular Recognition of an Adenine Derivative by Organoplatinum(II) Complexes with Hydrogen-Bonding Functionality

Abstract

The first examples of adenine binding by isomeric organoplatinum(II) complexes bearing H-bonding nicotinic and isonicotinic acid ligands are reported. Notably, a subtle switching of the H-bonding functionality from the 3- to 4-position of the pyridyl ring leads to a significant change in both the strength of association and the site of adenine binding.