|Title:||Investigating the Influence of Steric Hindrance on Selective Anion Transport|
|Authors:||Jowett, Laura A.|
Howe, Ethan N.W.
Gale, Philip A.
|Citation:||Jowett, L.A.; Ricci, A.; Wu, X.; Howe, E.N.W.; Gale, P.A. Investigating the Influence of Steric Hindrance on Selective Anion Transport. Molecules 2019, 24, 1278. https://doi.org/10.3390/molecules24071278|
|Abstract:||A series of symmetrical and unsymmetrical alkyl tren based tris-thiourea anion transporters were synthesised and their anion binding and transport properties studied. Overall, increasing the steric bulk of the substituents resulted in improved chloride binding and transport abilities. Including a macrocycle in the scaffold enhanced the selectivity of chloride transport in the presence of fatty acids, by reducing the undesired H+ flux facilitated by fatty acid flip-flop. This study demonstrates the benefit of including|
|Rights and Permissions:||CC BY 4.0|
|Type of Work:||Article|
|Type of Publication:||Publisher version|
|Appears in Collections:||Research Papers and Publications. Chemistry|
|molecules-24-01278.pdf||2.13 MB||Adobe PDF|
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