• Diversity and evolution of the animal virome 

      Harvey, Erin; Holmes, Edward C.
      Published 2022
      The COVID-19 pandemic has given the study of virus evolution and ecology new relevance. Although viruses were first identified more than a century ago, we likely know less about their diversity than that of any other ...
      Article
    • Understanding STEM academics' responses and resilience to educational reform of academic roles in higher education 

      Ross, Pauline Mary; Scanes, E.; Poronnik, P.; Coates, H.; Locke, W.
      Published 2022
      Background: Across the globe, there have been significant reforms to improve STEM education at all levels. A significant part of this has been teacher reform. While the responses and resilience of STEM teachers to educational ...
      Article
    • Virome characterization of game animals in China reveals a spectrum of emerging pathogens 

      He, Wan-Ting; Hou, Xin; Zhao, Jin; Sun, Jiumeng; He, Haijian; Si, Wei; Wang, Jing; Jiang, Zhiwen; Yan, Ziqing; Xing, Gang; Lu, Meng; Suchard, Marc A.; Ji, Xiang; Gong, Wenjie; He, Biao; Li, Jun; Lemey, Philippe; Guo, Deyin; Tu, Changchun; Holmes, Edward C.; Shi, Mang; Su, Shuo
      Published 2022
      Game animals are wildlife species traded and consumed as food, and potential reservoirs for SARS-CoV and SARS-CoV-2. We performed a meta-transcriptomic analysis of 1941 game animals, representing 18 species and five mammalian ...
      Article
    • Co-infection with SARS-COV-2 Omicron and Delta Variants Revealed by Genomic Surveillance 

      Rockett, Rebecca J; Draper, Jenny; Gall, Mailie; Sim, Eby M; Arnott, Alicia; Agius, Jessica E; Johnson-Mackinnon, Jessica; Martinez, Elena; Drew, Alexander P; Lee, Clement; Ngo, Christine; Ramsperger, Marc; Ginn, Andrew N; Wang, Qinning; Fennell, Michael; Ko, Danny; Huston, Linda; Kairaitis, Lukas; Holmes, Edward C.; O'Sullivan, Matthew N; Chen, Sharon C-A; Kok, Jen; Dwyer, Dominic E; Sintchenko, Vitali
      Published 2022
      We identified the co-infection of the SARS-CoV-2 Omicron and Delta variants in two epidemiologically unrelated patients with chronic kidney disease requiring haemodialysis. Both SARS-CoV-2 variants were co-circulating ...
      Preprint
    • Relating in vitro neutralisation level and protection in the CVnCoV (CUREVAC) trial. 

      Cromer, Deborah; Reynaldi, Arnold; Steain, Megan; Triccas, James A; Davenport, Miles P; Khoury, David S
      Published 2022
      The vaccine candidate CVnCoV (CUREVAC) showed surprisingly low efficacy in a recent phase 3 trial compared with other mRNA vaccines. Here we show that the low efficacy follows from the dose used and the presence of SARS-CoV-2 ...
      Article