Co-infection with SARS-COV-2 Omicron and Delta Variants Revealed by Genomic Surveillance
Type
PreprintAuthor/s
Rockett, Rebecca JDraper, Jenny
Gall, Mailie
Sim, Eby M
Arnott, Alicia
Agius, Jessica E
Johnson-Mackinnon, Jessica
Martinez, Elena
Drew, Alexander P
Lee, Clement
Ngo, Christine
Ramsperger, Marc
Ginn, Andrew N
Wang, Qinning
Fennell, Michael
Ko, Danny
Huston, Linda
Kairaitis, Lukas
Holmes, Edward C.
O'Sullivan, Matthew N
Chen, Sharon C-A
Kok, Jen
Dwyer, Dominic E
Sintchenko, Vitali
Abstract
We identified the co-infection of the SARS-CoV-2 Omicron and Delta variants in two epidemiologically unrelated patients with chronic kidney disease requiring haemodialysis. Both SARS-CoV-2 variants were co-circulating locally at the time of detection. Amplicon- and probe-based sequencing using short- and long-read technologies identified and quantified Omicron and Delta subpopulations in respiratory samples from the two patients. These findings highlight the importance of genomic surveillance in vulnerable populations.We identified the co-infection of the SARS-CoV-2 Omicron and Delta variants in two epidemiologically unrelated patients with chronic kidney disease requiring haemodialysis. Both SARS-CoV-2 variants were co-circulating locally at the time of detection. Amplicon- and probe-based sequencing using short- and long-read technologies identified and quantified Omicron and Delta subpopulations in respiratory samples from the two patients. These findings highlight the importance of genomic surveillance in vulnerable populations.
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Date
2022Share