Browsing Research Publications and Outputs by title
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[18F]AV-1451 PET in behavioural variant frontotemporal dementia due to MAPT mutation
Published 2016-10-18The validation of tau radioligands could improve the diagnosis of frontotemporal lobar degeneration and the assessment of disease-modifying therapies. Here, we demonstrate that binding of the tau radioligand [18F]AV-1451 ...Open AccessArticle -
3-dimensional NET image
Published 2021-03-29Z stacking of human Crohn's disease ileum specimen labelling neutrophil extracellular traps (NETs) structures including DNA, citrinillated H3, DNA, myeloperoxidase and neutrophil elastase. Image was labelled using a modified ...Open AccessAudiovisual -
Adding a diazo-transfer reagent to culture to generate secondary metabolite probes for click chemistry
Published 2022Converting discrete microbial metabolites into chemical probes for chemical biology and medicinal chemistry studies is typically preceded by lengthy purification and chemical derivatization processes. Standard practice ...Book chapter -
After the pandemic: perspectives on the future trajectory of COVID-19. [Review]
Published 2021There is a realistic expectation that the global effort in vaccination will bring the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic under control. Nonetheless, uncertainties remain about the type ...Article -
Alternatives to Student Outbound Mobility-Improving Students' Cultural Competency Skills Online to Improve Global Health Without Travel.
Published 2021Introduction Student outbound mobility is a major element in internationalization of medical education and global health education. However, this approach is often criticized, as it is inherently inequitable. Internationalization ...Article -
Antiviral cyclic peptides targeting the main protease of SARS-CoV-2
Published 2022Antivirals that specifically target SARS-CoV-2 are needed to control the COVID-19 pandemic. The main protease (Mpro) is essential for SARS-CoV-2 replication and is an attractive target for antiviral development. Here we ...Article -
Antiviral medications for preventing cytomegalovirus disease in solid organ transplant recipients
Published 2013-02-28Background The risk of cytomegalovirus (CMV) infection in solid organ transplant recipients has resulted in the frequent use of prophylaxis with the aim of preventing the clinical syndrome associated with CMV infection. ...Open AccessArticle -
Antiviral Medications for Preventing Cytomegalovirus Disease in Solid Organ Transplant Recipients
Published 2005-10-19Background: The risk of cytomegalovirus (CMV) infection in solid organ transplant recipients has resulted in the frequent use of prophylaxis with the aim of preventing the clinical syndrome associated with CMV infection. ...Open AccessArticle -
Assessment of amyloid β in pathologically confirmed frontotemporal dementia syndromes
Published 2017-05-29The diagnostic utility of in vivo amyloid β (Aβ) imaging to aid in the clinical distinction between frontotemporal dementia (FTD) and Alzheimer's disease remains unclear without data on the prevalence and severity of Aβ ...Open AccessArticle -
Assessment of Coronavirus Disease 2019 Intervention Strategies in the Nordic Countries Using Genomic Epidemiology
Published 2022We explored how the duration, size, and number of virus transmission clusters, defined as country-specific monophyletic groups in a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) phylogenetic tree, differed ...Article -
Azido-Desferrioxamine Siderophores as Functional Click-Chemistry Probes Generated in Culture upon Adding a Diazo-Transfer Reagent
Published 2020This work aimed to undertake the in situ conversion of the terminal amine groups of bacterial desferrioxamine (DFO) siderophores, including desferrioxamine B (DFOB), to azide groups to enable downstream click chemistry. ...Open AccessPre-print -
Barriers to the Professional Advancement of Women in Nephrology
Published 2019-07-26Open AccessArticle -
Co-infecting pathogens can contribute to inflammatory responses and severe symptoms in COVID-19
Published 2022Background: The current COVID-19 pandemic is posing a major challenge to public health on a global scale. While it is generally believed that severe COVID-19 results from over-expression of inflammatory mediators (i.e., a ...Article -
Co-infection with SARS-COV-2 Omicron and Delta Variants Revealed by Genomic Surveillance
Published 2022We identified the co-infection of the SARS-CoV-2 Omicron and Delta variants in two epidemiologically unrelated patients with chronic kidney disease requiring haemodialysis. Both SARS-CoV-2 variants were co-circulating ...Preprint -
Co-infection with SARS-CoV-2 Omicron and Delta variants revealed by genomic surveillance
Published 2022Co-infections with different variants of SARS-CoV-2 are a key precursor to recombination events that are likely to drive SARS-CoV-2 evolution. Rapid identification of such co-infections is required to determine their ...Article -
COVID-19 - lessons for zoonotic disease
Published 2022Disease emergence is driven by human-animal contact in a global viral ecosystem.Article -
A cross-study transcriptional analysis of Parkinson's disease
Published 2009-01-01The study of Parkinson's disease (PD), like other complex neurodegenerative disorders, is limited by access to brain tissue from patients with a confirmed diagnosis. Alternatively the study of peripheral tissues may offer ...Open AccessArticle -
The development and use of an anatomy-based retraining program (MusAARP) to assess and treat focal hand dystonia in musicians – a pilot study
Published 2021Background Movement dysfunctions are commonly reported in musicians, and in extreme cases may result in a persisting loss of motor control. This condition, whereby motor control of the hand during previously highly trained ...Article -
Discovery of Antiviral Cyclic Peptides Targeting the Main Protease of SARS-CoV-2 via mRNA Display
Published 2021Abstract Antivirals that specifically target SARS-CoV-2 are needed to control the COVID-19 pandemic. The main protease (M pro ) is essential for SARS-CoV-2 replication and is an attractive target for antiviral development. ...Preprint