Research Publications and Outputs: Recent submissions
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Disease-modifying drugs for knee osteoarthritis: can they be cost-effective?
Published 2013-05-01OBJECTIVE: Disease-modifying osteoarthritis drugs (DMOADs) are under development. Our goal was to determine efficacy, toxicity, and cost thresholds under which DMOADs would be a cost-effective knee OA treatment. DESIGN: ...Open AccessArticle -
Presence and Extent of Severe Facet Joint Osteoarthritis Are Associated with Back Pain in Older Adults
Published 2013-09-01Objective To determine whether the presence and extent of severe lumbar facet joint osteoarthritis (OA) are associated with back pain in older adults, accounting for disc height narrowing and other covariates. Design ...Open AccessArticle -
Structural correlates of pain in joints with osteoarthritis.
Published 2013-05-23Objective: To describe the insights on the epidemiology of pain-structure association and the ramifications of these studies for clinical trials. Design: Narrative review summarizing the pertinent literature in this area, ...Open AccessArticle -
ERCC1 expression and RAD51B activity correlate with cell cycle response to platinum drug treatment not DNA repair
Published 2008-06-25Background: The H69CIS200 and H69OX400 cell lines are novel models of low- level platinum-drug resistance. Resistance was not associated with increased cellular glutathione or decreased accumulation of platinum, rather the ...Open AccessArticle -
Regrowth resistance: low-level platinum resistance mediated by rapid recovery from platinum-induced cell-cycle arrest
Published 2009-01-01The H69CIS200 and H69OX400 cell lines are novel models of low-level platinum drug resistance developed from H69 human small-cell lung cancer cells with eight 4-day treatments of 200 ng/ml cisplatin and 400 ng/ml oxaliplatin, ...Open AccessBook chapter