Studies of the labile lead pool using a rhodamine-based fluorescent probe
| Field | Value | Language |
| dc.contributor.author | Zhu, Jianping | |
| dc.contributor.author | Yeo, Jia Hao | |
| dc.contributor.author | Bower, Amy A | |
| dc.contributor.author | Proschogo, Nicholas | |
| dc.contributor.author | New, Elizabeth J | |
| dc.date.accessioned | 2021-12-03T03:45:08Z | |
| dc.date.available | 2021-12-03T03:45:08Z | |
| dc.date.issued | 2020 | en_AU |
| dc.identifier.uri | https://hdl.handle.net/2123/27121 | |
| dc.description.abstract | Lead is a heavy metal which has long been known to have toxic effects on the body. However, much remains to be learnt about the labile lead pool and cellular uptake of lead. We report here RPb1 that undergoes a 100-fold increase in fluorescence emission in the presence of Pb2+, and which can be applied to study the labile lead pool within cells. We demonstrate the capacity of RPb1 for investigating labile lead pool in DLD-1 cells and changes in labile lead during differentiation of K562 cells. | en_AU |
| dc.language.iso | en | en_AU |
| dc.publisher | Royal Society of Chemistry | en_AU |
| dc.relation.ispartof | Metallomics | en_AU |
| dc.rights | Creative Commons Attribution-NonCommercial 4.0 | en_AU |
| dc.title | Studies of the labile lead pool using a rhodamine-based fluorescent probe | en_AU |
| dc.type | Article | en_AU |
| dc.subject.asrc | 0302 Inorganic Chemistry | en_AU |
| dc.subject.asrc | 0304 Medicinal and Biomolecular Chemistry | en_AU |
| dc.subject.asrc | 0305 Organic Chemistry | en_AU |
| dc.identifier.doi | 10.1039/d0mt00056f | |
| dc.type.pubtype | Author accepted manuscript | en_AU |
| dc.relation.arc | DP180101353 | |
| usyd.faculty | SeS faculties schools::Faculty of Science::School of Chemistry | en_AU |
| usyd.citation.volume | 12 | en_AU |
| usyd.citation.issue | 5 | en_AU |
| usyd.citation.spage | 644 | en_AU |
| usyd.citation.epage | 648 | en_AU |
| workflow.metadata.only | No | en_AU |
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