Efficient radiosynthesis of a [18F]-phosphonium salt containing closo-carborane
Access status:
Open Access
Type
ArticleAuthor/s
Ioppolo, Joseph A.Giboureau, Nicolas
Bhadbhade, Mohan
Morrison, Daniel E.
Kassiou, Michael
Rendina, Louis M.
Abstract
An efficient synthesis of an 18F-labelled phosphonium salt containing closo-carborane is described. The preparation of this salt was attempted using both single-step and two-step protocols, with greater success found for the latter. An X-ray structure for the unlabelled 19F salt is also presented.An efficient synthesis of an 18F-labelled phosphonium salt containing closo-carborane is described. The preparation of this salt was attempted using both single-step and two-step protocols, with greater success found for the latter. An X-ray structure for the unlabelled 19F salt is also presented.
See less
See less
Date
2017-11-15Publisher
ElsevierLicence
OtherFaculty/School
Faculty of Science, School of ChemistryCitation
Tetrahedron Letters 58 (2017) 4367–4371Share