• Cyclisation strategies for stabilising peptides with irregular conformations 

      Vu, Quynh Ngoc; Young, Reginald; Sudhakar, Haritha Krishna; Gao, Tianyi; Huang, Tiancheng; Tan, Yaw Sing
      Published 2021
      Cyclisation is a common synthetic strategy for enhancing the therapeutic potential of peptide-based molecules. While there are extensive studies on peptide cyclisation for reinforcing regular secondary structures such as ...
      Open Access
      Article
    • Encapsulin Nanocompartments for Biomanufacturing Applications 

      Szyszka, Taylor; Adamson, Lachlan; Lau, Yu Heng
      Published 2022
      Enzyme scaffolding is an emerging technique for enhancing yield and efficiency of biomanufacturing processes for generating high-value products. Of the many scaffolds available for in vivo and cell-free applications, ...
      Open Access
      Book chapter
    • How Pore Architecture Regulates the Function of Nanoscale Protein Compartments 

      Tasneem, Nuren; Szyszka, Taylor; Jenner, Eric; Lau, Yu Heng
      Published 2022
      Self-assembling proteins can form porous compartments that adopt well-defined architectures at the nanoscale. In nature, protein compartments act as semipermeable barriers to enable spatial separation and organization of ...
      Open Access
      Article