School of Chemistry: Recent submissions
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Full elucidation of the transmembrane anion transport mechanism of squaramides using in silico investigations
Published 2018-01-01A comprehensive experimental and theoretical investigation of the transmembrane chloride transport promoted by four series of squaramide derivatives, with different degrees of fluorination, number of convergent N–H binding ...Open AccessArticle -
Anion transport by ortho-phenylene bis-ureas across cell and vesicle membranes
Published 2017-12-01Ortho-Phenylene bis-ureas serve as anionophores in cells expressing halide-sensitive yellow fluorescent protein, as well as in synthetic vesicles. Activities can reach high levels, and are strongly dependent on the ...Open AccessArticle -
Fluorescent squaramides as anion receptors and transmembrane anion transporters
Published 2018-01-01A series of squaramide-based anion transporters functionalised with the 1,8-naphthalimide fluorophore has been developed for improved ionophoric activity and fluorescent imaging in cells.Open AccessArticle -
Cyclic peptide unguisin A is an anion receptor with high affinity for phosphate and pyrophosphate
Published 2017-02-01Unguisin A (1) is a marine-derived, GABA-containing cyclic heptapeptide. The biological function of this flexible macrocycle is obscure. Here we show that compound 1 lacks any detectable activity in antimicrobial growth ...Open AccessArticle -
Anion transport and supramolecular medicinal chemistry
Published 2017-01-01New approaches to the transmembrane transport of anions are discussed in this review. Advances in the design of small molecule anion carriers are reviewed in addition to advances in the design of synthetic anion channels. ...Open AccessArticle