School of Chemistry: Recent submissions
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Transporter and protease mediated delivery of platinum complexes for precision oncology
Published 2019-01-01Precision approaches are rapidly becoming the norm in the treatment of cancer and this is already impacting on the way platinum complexes are used. In this commentary, we will argue that there is the potential for platinum ...Open AccessArticle -
Remarkable Enhancement in Boron Uptake Within Glioblastoma Cells With Carboranyl-Indole Carboxamides
Published 2018-10-17Novel boron‐rich, carboranyl–indole carboxamide ligands were prepared and found to effectively target the 18 kDa translocator protein (TSPO), an upregulated mitochondrial membrane‐bound protein which has been observed in ...Open AccessArticle -
High mitochondrial accumulation of new gadolinium(III) agents within tumour cells
Published 2014-01-01The first bifunctional Gd(III) complexes covalently bound to arylphosphonium cations and the first tumour-cell selective mitochondrial agents designed for potential application in binary cancer therapies are reported. The ...Open AccessArticle -
Carborane functionalization of the aromatic network in chemically-synthesized graphene
Published 2014-08-06The conjugated aromatic system of graphene was used to trap the reactive, boron-rich 1,2-carborane cluster. Functionalization of the graphene surface was confirmed by solid-state MAS 11B NMR spectroscopy and quantified by ...Open AccessArticle -
Molecular Recognition of an Adenine Derivative by Organoplatinum(II) Complexes with Hydrogen-Bonding Functionality
Published 2019-03-15The first examples of adenine binding by isomeric organoplatinum(II) complexes bearing H-bonding nicotinic and isonicotinic acid ligands are reported. Notably, a subtle switching of the H-bonding functionality from the 3- ...Open AccessArticle