School of Chemistry: Recent submissions
-
Synthesis of nitro-aryl functionalised 4-amino-1,8-naphthalimides and their evaluation as fluorescent hypoxia sensors
Published 2020Fluorescent sensors are a vital research tool, enabling the study of intricate cellular processes in a sensitive manner. The design and synthesis of responsive and targeted probes is necessary to allow such processes to ...Open AccessArticle -
Elucidating the Roles of Fenton Reactants in Drug-Treated Cells using a Selective Rhodamine-Thiophenol Fluorogenic Sensor
Published 2021While Fenton chemistry has long been known to play a role in inducing cellular stress, there has been recent renewed interest in understanding its roles in health and disease. Here we describe a fluorogenic probe, RTFt1, ...Open AccessArticle -
Strategies for organelle targeting of fluorescent probes
Published 2021Fluorescent tools have emerged as an important tool for studying the distinct chemical microenvironments of organelles, due to their high specificity and ability to be used in non-destructive, live cellular ...Open AccessArticle -
Dual-functionalisation of fluorophores for the preparation of targeted and selective probes
Published 2020A key current challenge in biological research is the elucidation of the roles that chemicals and chemical reactions play in cellular function and dysfunction. Of the available cellular imaging techniques, ...Open AccessArticle -
Nicotinamide-appended fluorophores as fluorescent redox sensors
Published 2019Fluorescent sensors have proved invaluable in elucidating the regulation and dysregulation of redox processes in biology, but understanding of the breadth of biological redox reactions requires development of new sensors ...Open AccessArticle