School of Chemistry: Recent submissions
-
Crown ether-thiourea conjugates as ion transporters
Published 2022Na+, Cl− and K+ are the most abundant electrolytes present in biological fluids that are essential to the regulation of pH homeostasis, membrane potential and cell volume in living organisms. Herein, we report synthetic ...Open AccessArticle -
The impact of highly electron withdrawing carboxylato ligands on the stability and activity of platinum(IV) pro-drugs
Published 2019Recent developments in the design of platinum(IV) pro-drug candidates have demonstrated the importance of the coordination sphere of the complex in determining the resistance to reduction by endogenous reductants and the ...Open AccessArticle -
The effect of charge on the uptake and resistance to reduction of platinum(IV) complexes in human serum and whole blood models
Published 2020cis- and trans-Platinum(IV) complexes with diaminetetracarboxylate coordination spheres possess the highly desirable property of exhibiting unusual resistance to reduction by blood serum components and endogenous reductants ...Open AccessArticle -
Studies of the labile lead pool using a rhodamine-based fluorescent probe
Published 2020Lead is a heavy metal which has long been known to have toxic effects on the body. However, much remains to be learnt about the labile lead pool and cellular uptake of lead. We report here RPb1 that undergoes a 100-fold ...Open AccessArticle -
Duale Funktionalisierung von Fluorophoren für die Konstruktion zielgerichteter und selektiver Fluoreszenz-Sensoren
Published 2020Eine Schlüsselfrage in der gegenwärtigen biologischen Forschung ist, welche Rolle gewisse Chemikalien und chemische Reaktionen im Zusammenhang mit dem regulären zellulären Betrieb, als auch mit zellulären Störungen spielen. ...Open AccessArticle