Faculty of Science: Recent submissions
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Remarkable Enhancement in Boron Uptake Within Glioblastoma Cells With Carboranyl-Indole Carboxamides
Published 2018-10-17Novel boron‐rich, carboranyl–indole carboxamide ligands were prepared and found to effectively target the 18 kDa translocator protein (TSPO), an upregulated mitochondrial membrane‐bound protein which has been observed in ...Open AccessArticle -
High mitochondrial accumulation of new gadolinium(III) agents within tumour cells
Published 2014-01-01The first bifunctional Gd(III) complexes covalently bound to arylphosphonium cations and the first tumour-cell selective mitochondrial agents designed for potential application in binary cancer therapies are reported. The ...Open AccessArticle -
Carborane functionalization of the aromatic network in chemically-synthesized graphene
Published 2014-08-06The conjugated aromatic system of graphene was used to trap the reactive, boron-rich 1,2-carborane cluster. Functionalization of the graphene surface was confirmed by solid-state MAS 11B NMR spectroscopy and quantified by ...Open AccessArticle -
Molecular Recognition of an Adenine Derivative by Organoplatinum(II) Complexes with Hydrogen-Bonding Functionality
Published 2019-03-15The first examples of adenine binding by isomeric organoplatinum(II) complexes bearing H-bonding nicotinic and isonicotinic acid ligands are reported. Notably, a subtle switching of the H-bonding functionality from the 3- ...Open AccessArticle -
The first indoleamine-2,3-dioxygenase-1 (IDO1) inhibitors containing carborane
Published 2014-04-22Indoleamine-2,3-dioxygenase-1 (IDO1) is a critical immunoregulatory enzyme responsible for the metabolism of tryptophan during inflammation and disease. Based upon a pyranonaphthoquinone framework, the first examples of ...Open AccessArticle