Faculty of Science: Recent submissions
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Synthesis and DNA-binding studies of a dinuclear gadolinium(III)-platinum(II) complex
Published 2015-01-27The synthesis and characterisation of a new dinuclear GdIII–PtII complex (1·PF6) containing a functionalised macrocyclic 1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid derivative linked to a PtII-terpy (terpy = 2,2′ ...Open AccessArticle -
Synthesis and biological evaluation of a class of mitochondrially-targeted gadolinium(III) agents
Published 2014-10-16A structure–activity relationship study of a library of novel bifunctional GdIII complexes covalently linked to arylphosphonium cations is reported. Such complexes have been designed for potential application in binary ...Open AccessArticle -
Synthesis and stability studies of Ga-67 labeled phosphonium salts
Published 2017-11-07Delocalized lipophilic cations such as tri‐ and tetra‐arylphosphonium are able to diffuse across the mitochondrial membrane, which allows them to selectively accumulate in cells with a high transmembrane potential (ΔΨm). ...Open AccessArticle -
Syntheses and reductions of C-dimesitylboryl-1,2-dicarba-closo-dodecaboranes
Published 2015-04-24Two C-dimesitylboryl-1,2-dicarba-closo-dodecaboranes, 1-(BMes2)-2-R-1,2-C2B10H10 (1, R = H, 2, R = Ph), were synthesised by lithiation of 1,2-dicarba-closo-dodecaborane and 1-phenyl-1,2-dicarba-closo-dodecaborane, respectively, ...Open AccessArticle -
Tumor cell uptake and selectivity of gadolinium(III)-phosphonium complexes: The role of delocalisation at the phosphonium centre
Published 2017-12-01The synthesis of a series of bifunctional Gd(III) complexes 1–3 covalently bound to arylphosphonium cations possessing a varying degree of delocalisation at the phosphonium centre is presented. The influence of the degree ...Open AccessArticle