Gale, Philip A.; Howe, Ethan N.W.; Wu, Xin; Spooner, Michael J.(Elsevier, 2018-02)
This review covers recent advances in anion receptor chemistry from 2016, including developments in
self-assembly, sensing, anion separation, transport, catalysis and fundamental advances in anion recognition
Yang, Yufeng; Wu, Xin; Busschaert, Nathalie; Furuta, Hiroyuki; Gale, Philip A.(Royal Society of Chemistry, 2017-07)
A systematic study of chloride vs. nitrate selectivity across six anion
transporters has revealed a good correlation between the selectivities
of their anion binding and membrane transport properties. This work
Spooner, Michael J.; Li, Hongyu; Marques, Igor; Costa, Pedro M.R.; Wu, Xin; Howe, Ethan N.W.; Busschaert, Nathalie; Moore, Stephen J.; Light, Mark E.; Sheppard, David N.; Gale, Philip A.(Royal Society of Chemistry, 2018)
A series of fluorinated tripodal tris-thioureas function as highly active anion transporters across lipid bilayers and cell membranes. Here, we investigate their mechanism of action using anion transport assays in cells ...
Jowett, Laura A.; Ricci, Angela; Wu, Xin; Howe, Ethan N.W.; Gale, Philip A.(MDPI, 2019-04-02)
A series of symmetrical and unsymmetrical alkyl tren based tris-thiourea anion transporters
were synthesised and their anion binding and transport properties studied. Overall, increasing the
steric bulk of the substituents ...
Jowett, Laura A.; Howe, Ethan N.W.; Wu, Xin; Busschaert, Nathalie; Gale, Philip A.(Wiley VCH, 2018-06-19)
The anion transport properties of a series of previously
reported tren-based anionophores have been revisited
using new assays designed to measure anion uniport. This
study provides new insights into the transport ...
Wu, Xin; Wang, Patrick; Turner, Peter; Lewis, William; Catal, Osman; Thomas, Donald S.; Gale, Philip A.(Cell Press, 2019-05-09)
Artificial receptors that recognize anionic species via non-covalent interactions have a wide range of biomedical, industrial, and environmental applications. A major challenge in this area of research is to achieve ...
Wu, Xin; Small, Jennifer R.; Cataldo, Alessio; Withecombe, Anne M.; Turner, Peter; Gale, Philip A.(Wiley-VCH, 2019-08-30)
Synthetic anion transporters that facilitate transmembrane H+/Cl- symport (cotransport) have anti-cancer
potential due to their ability to neutralize pH gradients and inhibit autophagy in cells. However, compared to the ...