Presence and Extent of Severe Facet Joint Osteoarthritis Are Associated with Back Pain in Older Adults
Field | Value | Language |
dc.contributor.author | Suri, Pradeep | |
dc.contributor.author | Hunter, David J. | |
dc.contributor.author | Rainville, James | |
dc.contributor.author | Guermazi, Ali | |
dc.contributor.author | Katz, Jeffrey N. | |
dc.date.accessioned | 2014-01-28 | |
dc.date.available | 2014-01-28 | |
dc.date.issued | 2013-09-01 | |
dc.identifier.citation | P. Suri, D.J. Hunter, J. Rainville, A. Guermazi, J.N. Katz, Presence and extent of severe facet joint osteoarthritis are associated with back pain in older adults, Osteoarthritis and Cartilage, Volume 21, Issue 9, September 2013, Pages 1199-1206, | en_AU |
dc.identifier.issn | 1063-4584 | |
dc.identifier.uri | http://hdl.handle.net/2123/9950 | |
dc.description.abstract | Objective To determine whether the presence and extent of severe lumbar facet joint osteoarthritis (OA) are associated with back pain in older adults, accounting for disc height narrowing and other covariates. Design Two hundred and fifty-two older adults from the Framingham Offspring Cohort (mean age 67 years) were studied. Participants received standardized computed tomography (CT) assessments of lumbar facet joint OA and disc height narrowing at the L2–S1 interspaces using four-grade semi-quantitative scales. Severe facet joint OA was defined according to the presence and/or degree of joint space narrowing, osteophytosis, articular process hypertrophy, articular erosions, subchondral cysts, and intraarticular vacuum phenomenon. Severe disc height narrowing was defined as marked narrowing with endplates almost in contact. Back pain was defined as participant report of pain on most days or all days in the past 12 months. We used multivariable logistic regression to examine associations between severe facet joint OA and back pain, adjusting for key covariates including disc height narrowing, sociodemographics, anthropometrics, and health factors. Results Severe facet joint OA was more common in participants with back pain than those without (63.2% vs 46.7%; P = 0.03). In multivariable analyses, presence of any severe facet joint OA remained significantly associated with back pain (odds ratio (OR) 2.15 [95% confidence interval (CI) 1.13–4.08]). Each additional joint with severe OA conferred greater odds of back pain [OR per joint 1.20 (95% CI 1.02–1.41)]. Conclusions The presence and extent of severe facet joint OA on CT imaging are associated with back pain in community-based older adults, independent of sociodemographics, health factors, and disc height narrowing. | en_AU |
dc.language.iso | en | en_AU |
dc.publisher | Elsevier | en_AU |
dc.relation | The National Heart, Lung and Blood Institute's Framingham Heart Study contract (No. N01-HC-25195) supported the recruitment, enrollment, and examination of the Offspring and Third Generation Cohorts and the CT scans. Dr. Suri and this research were funded by the Rehabilitation Medicine Scientist Training Program (RMSTP) and the National Institutes of Health (K12 HD 01097), with supplemental funding from the New England Baptist Hospital Research Funding Award and the Elizabeth Stent Fund. Dr. Katz was funded in part by NIH/NIAMSK24 AR 02123 and NIH/NIAMS P60 AR 47782. Dr. Hunter is funded by an Australian Research Council Future Fellowship. | en_AU |
dc.subject | Osteoarthritis | en_AU |
dc.title | Presence and Extent of Severe Facet Joint Osteoarthritis Are Associated with Back Pain in Older Adults | en_AU |
dc.type | Article | en_AU |
dc.subject.asrc | FoR::110322 - Rheumatology and Arthritis | en_AU |
dc.identifier.doi | http://dx.doi.org/10.1016/j.joca.2013.05.013 | |
dc.type.pubtype | Post-print | en_AU |
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