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    • (4,7-Dimethyl-1,10-phenanthroline (ethylenediamine) platinum(II) dichloride tris(deuterium oxide) solvate 

      Brodie, Craig R.; Turner, Peter; Wheate, Nial J.; Aldrich-Wright, Janice R.
      Published 2006-01-01
      Open Access
      Article
      View
    • Adjudicated dataset for “Spin” in published biomedical literature: A methodological systematic review 

      Bero, Lisa; Grundy, Quinn; Chiu, Kellia
      Published 2017-06-13
      This dataset contains the findings of a systematic review of the nature and prevalence of spin in the biomedical literature. It contains the data from 35 empirical studies that included the measurement of spin for at least ...
      Open Access
      Dataset
      View
    • Advancing health care resilience through a systems-based collaborative approach: Lessons learned from COVID-19 

      Khalili, Hossein; Lising, Dean; Kolcu, Giray; Thistlethwaite, Jill; Gilbert, John; Langlois, Sylvia; Maxwell, Barbara; Kolcu, Mukadder İnci Başer; MacMillan, Kathleen M; Schneider, Carl; Freire Filho, José Rodrigues; Najjar, Ghaidaa; Al-Hamdan, Zaid; Pfeifle, Andrea
      Published 2021
      Article
      View
    • An analysis of the experimental and theoretical charge density distributions of the piroxicam-saccharin co-crystal and its constituents 

      Du, Jonathan J.; Váradi, Linda; Williams, Peter A.; Groundwater, Paul W.; Overgaard, Jacob; Platts, James A.; Hibbs, David E.
      Published 2016-05-02
      Experimental and theoretical charge density analyses of piroxicam (1), saccharin (2) and their 1:1 co-crystal complex (3) have been carried out. Electron density distribution (EDD) was determined through the use of ...
      Open Access
      Article
      View
    • Australian Poisoning Surveillance Initiative (APSI) Databank 

      Cairns, Rose; Buckley, Nicholas; Dzidowska, Monika; Benger, Lauren; Roberts, Darren; Wright, Nicole; Wylie, Carol; Elliott, Rohan; Greene, Shaun; Dean, Danielle; Heiner, Madeline; Armstrong, Jason; Isoardi, Katherine; Chiew, Angela; Brown, Jared; Dawson, Andrew; Merwood, Nick; Soderstrom, Jessamine
      Published 2024-11-26
      The APSI Databank is a de-identified dataset derived from calls logged by poisons specialists working at Australian Poisons Information Centres (PICs) during routine clinical operations. This includes data on calls from ...
      Dataset
      View
    • Biologics and Vaccines for Nasal and Pulmonary Drug Delivery 

      Komalla, Varsha; Haghi, Mehra; Kayser, Veysel
      Published 2022
      Biologics are a rapidly emerging class of therapeutics that have succeeded clinically and commercially due to their specificity and efficacy against various diseases including cancer, inflammatory, and autoimmune diseases. ...
      Book chapter
      View
    • Broad Decline in Viral Infections During COVID-19 Lockdown: Association with Lung Function in Lung Transplant Recipients 

      de Zwart, A.E.; Riezebos-Brilman, A.; Lunter, G.; Neerken, E.; Van Leer, C.; Alffenaar, J.C.; Van Gemert, J.P.; Erasmus, M.E.; Gan, C.T.; Kerstjens, H.A.; Vonk, J.M.; Verschuuren, E.A.
      Published 2022
      Purpose In April 2020 COVID-19 lockdown measures were instigated leading to a dramatic drop in non-COVID respiratory virus infections (RVI). This provided a unique situation to assess the impact of RVI on annual FEV1 ...
      Article
      View
    • Burnout and the challenges facing pharmacists during COVID-19: results of a national survey 

      Johnston, Karlee; O’Reilly, Claire L.; Scholz, Brett; Georgousopoulou, Ekavi N.; Mitchell, Imogen
      Published 2021
      Background COVID-19 has impacted the psychological wellbeing of healthcare workers and has forced pharmacists to adapt their services. Objective To measure burnout and describe the work and psychosocial factors affecting ...
      Article
      View
    • Can krill oil from small crustaceans be a panacea that alleviates symptoms of knee osteoarthritis? 

      Vitetta, Luis
      Published 2022
      For decades fish oils have been promoted as important for health, and currently it is well known that the long-chain omega-3 (n–3) fatty acids, EPA and DHA, are fats with essential considerations for health (1, 2). A wide ...
      Open Access
      Article
      View
    • Can ultrasound novices develop image acquisition skills after reviewing online ultrasound modules? 

      Situ-LaCasse, Elaine; Acuña, Josie; Huynh, Dang; Amini, Richard; Irving, Steven; Samsel, Kara; Patanwala, Asad E.; Biffar, David E.; Adhikari, Srikar
      Published 2021
      BackgroundPoint-of-care ultrasound is becoming a ubiquitous diagnostic tool, and there has been increasing interest to teach novice practitioners. One of the challenges is the scarcity of qualified instructors, and with ...
      Article
      View
    • A chemical preformulation study of a host–guest complex of cucurbit[7]uril and a multinuclear platinum agent for enhanced anticancer drug delivery 

      Kennedy, Alan R.; Florence, Alastair J.; McInnes, Fiona J.; Wheate, Nial J.
      Published 2009-01-01
      Single crystal and powder X-ray diffraction have been used to examine the host–guest complex of cucurbit[7]uril (CB[7]) and the model dinuclear platinum anticancer complex trans-[{PtCl(NH3)2}2μ-dpzm]2+ (di-Pt, dpzm= ...
      Open Access
      Article
      View
    • Ciprofloxacin nanocrystals liposomal powders for controlled drug release via inhalation 

      Khatib, Isra; Khanal, Dipesh; Ruan, Juanfang; Cipolla, David; Dayton, Francis; Blanchard, James; Chan, Hak-Kim
      Published 2019
      This study was conducted to evaluate the feasibility of developing inhalable dry powders of liposomal encapsulated ciprofloxacin nanocrystals (LECN) for controlled drug release. Dry powders of LECN were produced by freeze-thaw ...
      Open Access
      Article
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    • Cisplatin drug delivery using gold-coated iron oxide nanoparticles for enhanced tumour targeting with external magnetic fields 

      Wagstaff, Amelia A.; Brown, Sarah D.; Holden, Megan R.; Craig, Gemma E.; Plumb, Jane A.; Brown, Roisin E.; Schreiter, Norbert; Chrzanowski, Wojciech; Wheate, Nial J.
      Published 2012-05-30
      The platinum-based chemotherapeutic drug cisplatin is highly effective in the treatment of solid tumours, but its use is restricted by poor bioavailability, severe dose-limiting side effects and rapid development of drug ...
      Open Access
      Article
      View
    • A cisplatin slow-release hydrogel drug delivery system based on a formulation of the macrocycle cucurbit[7]uril, gelatin and polyvinyl alcohol 

      Oun, Rabbab; Plumb, Jane; Wheate, Nial
      Published 2014-02-18
      The anticancer drug cisplatin was encapsulated within the cucurbit[7]uril macrocycle to form the host-guest complex: cisplatin@CB[7]. This was then incorporated into gelatin and 0–4% w/v polyvinyl alcohol (PVA)- based ...
      Open Access
      Article
      View
    • Cisplatin-Tethered Gold Nanoparticles That Exhibit Enhanced Reproducibility, Drug Loading, and Stability: a Step Closer to Pharmaceutical Approval? 

      Craig, Gemma E.; Brown, Sarah D.; Lamprou, Dimitrios A.; Graham, Duncan; Wheate, Nial J.
      Published 2012-03-05
      Gold nanoparticles (AuNPs) can be used as delivery vehicles for platinum anticancer drugs, improving their targeting and uptake into cells. Here, we examine the appropriateness of different-sized AuNPs as components of ...
      Open Access
      Article
      View
    • Combining aspects of the platinum anticancer drugs picoplatin and BBR3464 to synthesize a new family of sterically hindered dinuclear complexes; their synthesis, binding kinetics and cytotoxicity 

      Brown, Sarah D.; Trotter, Katherine D.; Sutcliffe, Oliver B.; Plumb, Jane A.; Waddell, Bruce; Briggs, Naomi E. B.; Wheate, Nial J.
      Published 2012-07-12
      Picoplatin is a sterically hindered mononuclear platinum drug undergoing clinical trials. The 2-methylpyridine ring provides steric hindrance to the drug, preventing attack from biological nucleophiles. BBR3464 is a ...
      Open Access
      Article
      View
    • Comment on: Cannabis use among Danish patients with cancer: a cross‑sectional survey of sociodemographic traits, quality of life, and patient experiences. 

      Vitetta, Luis; Sikali, Jason F; Fletcher, Courtney; Henson, Jeremy D
      Published 2022
      The recent article by Nielsen and colleagues [1] presents an interesting cross-sectional investigation on a subgroup of cancer patients that self-prescribed cannabinoids. The authors present a study with a high response ...
      Open Access
      Article, Letter
      View
    • Comparison of preprints and final journal publications from COVID-19 Studies: Discrepancies in results reporting and spin in interpretation 

      Bero, Lisa; Lawrence, Rosa; Leslie, Louis; Chiu, Kellia; McDonald, Sally; Page, Matthew J; Grundy, Quinn; Parker, Lisa; Boughton, Stephanie L; Kirkham, Jamie J; Featherstone, Robin
      Published 2021
      ABSTRACT Objective To compare results reporting and the presence of spin in COVID-19 study preprints with their finalized journal publications Design Cross-sectional Setting International medical literature Participants ...
      Preprint
      View
    • A comparison of the experimental and theoretical charge density distributions in two polymorphic modifications of Piroxicam. 

      Lai, Felcia; Du, Jonathan J.; Williams, Peter A.; Váradi, Linda; Baker, Daniel; Groundwater, Paul W.; Overgaard, Jacob; Platts, James A.; Hibbs, David E.
      Published 2016-04-28
      Experimental charge density distribution studies of two polymorphic forms of piroxicam, β- piroxicam (1) and piroxicam monohydrate (2), were carried out via high-resolution single crystal X-ray diffraction experiments and ...
      Open Access
      Article
      View
    • Consumer Perspectives of the Australian Home Medicines Review Program: Benefits and Barriers 

      White, Lesley; Klinner, Christiane; Carter, Stephen R
      Published 2012-01-01
      BACKGROUND: The Australian Home Medicines Review (HMR) is a free consumer service to assist individuals living at home to maximize the benefits of their medicine regimen and prevent medication related problems. It consists ...
      Open Access
      Article
      View
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