Research Publications and Outputs: Recent submissions

    • Epidemiological Approaches to Understanding the Link Between Type 2 Diabetes and Dementia. 

      Sutherland, GT; Lim, J; Srikanth, V; Bruce, DG
      Published 2017-01-01
      Diabetes and dementia are two diseases that increased dramatically in most societies in direct proportion to increases in average life expectancy. The two conditions are strongly associated and there is much hope that ...
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    • Evidence supporting oxidative stress in a moderately affected area of the brain in Alzheimer’s disease 

      Youssef, P; Chami, B; Lim, J; Middleton, T; Sutherland, GT; Witting, PK
      Published 2018-08-01
      The pathogenesis of Alzheimer's disease (AD) remains to be elucidated. Oxidative damage and excessive beta-amyloid oligomers are components of disease progression but it is unclear how these factors are temporally related. ...
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    • Re-investigating the effects of chronic smoking on the pathology of alcohol-related human brain damage 

      McCorkindale, AN; Sizemova, A; Sheedy, D; Kril, JJ; Sutherland, GT
      Published 2018-07-01
      Both pathological and neuroimaging studies have shown that chronic alcohol abuse causes generalized white matter, but limited gray matter, volume loss. Recent neuroimaging studies suggest that tobacco smoking also causes ...
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    • Identification of an immune modulation locus utilising a bovine mammary gland infection challenge model 

      Littlejohn, MD; Turner, SA; Walker, CG; Berry, SD; Tiplady, K; Sherlock, RG; Sutherland, GT; Swift, S; Garrick, D; Lacy-Hulbert, SJ; McDougall, S; Spelman, RJ; Snell, RG; Hillerton, JE
      Published 2018-01-01
      Inflammation of the mammary gland following bacterial infection, commonly known as mastitis, affects all mammalian species. Although the aetiology and epidemiology of mastitis in the dairy cow are well described, the genetic ...
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    • A large-scale genetic association study to evaluate the contribution of Omi/HtrA2 (PARK13) to Parkinson's disease 

      Krüger, R; Sharma, M; Riess, O; Gasser, T; Van Broeckhoven, C; Theuns, J; Aasly, J; Annesi, G; Bentivoglio, AR; Brice, A; Djarmati, A; Elbaz, A; Farrer, M; Ferrarese, C; Gibson, JM; Hadjigeorgiou, GM; Hattori, N; Ioannidis, JP; Jasinska-Myga, B; Klein, C; Lambert, JC; Lesage, S; Lin, JJ; Lynch, T; Mellick, GD; de Nigris, F; Opala, G; Prigione, A; Quattrone, A; Ross, OA; Satake, W; Silburn, PA; Tan, EK; Toda, T; Tomiyama, H; Wirdefeldt, K; Wszolek, Z; Xiromerisiou, G; Maraganore, DM
      Published 2011-01-01
      High-profile studies have provided conflicting results regarding the involvement of the Omi/HtrA2 gene in Parkinson's disease (PD) susceptibility. Therefore, we performed a large-scale analysis of the association of common ...
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