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School of Medical Sciences: Recent submissions

    • A large-scale genetic association study to evaluate the contribution of Omi/HtrA2 (PARK13) to Parkinson's disease 

      Krüger, R; Sharma, M; Riess, O; Gasser, T; Van Broeckhoven, C; Theuns, J; Aasly, J; Annesi, G; Bentivoglio, AR; Brice, A; Djarmati, A; Elbaz, A; Farrer, M; Ferrarese, C; Gibson, JM; Hadjigeorgiou, GM; Hattori, N; Ioannidis, JP; Jasinska-Myga, B; Klein, C; Lambert, JC; Lesage, S; Lin, JJ; Lynch, T; Mellick, GD; de Nigris, F; Opala, G; Prigione, A; Quattrone, A; Ross, OA; Satake, W; Silburn, PA; Tan, EK; Toda, T; Tomiyama, H; Wirdefeldt, K; Wszolek, Z; Xiromerisiou, G; Maraganore, DM
      Published 2011-01-01
      High-profile studies have provided conflicting results regarding the involvement of the Omi/HtrA2 gene in Parkinson's disease (PD) susceptibility. Therefore, we performed a large-scale analysis of the association of common ...
      Open Access
      Article
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    • Lack of reproducibility in re-evaluating associations between GCH1 polymorphisms and Parkinson's disease and isolated dystonia in an Australian case--control group. 

      Newman, JR; Todorovic, M; Silburn, PA; Sutherland, GT; Mellick, GD
      Published 2014-01-01
      Open Access
      Article
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    • Exploiting the potential of molecular profiling in Parkinson's disease: current practice and future probabilities 

      Mellick, GD; Silburn, PA; Sutherland, GT; Siebert, GA
      Published 2010-01-01
      Parkinson's disease (PD) is a common, heterogeneous syndrome diagnosed clinically by the presence of classical neurological symptoms and the absence of 'red flags' that suggest alternative secondary parkinsonian disorders. ...
      Open Access
      Article
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    • Human adult neurogenesis across the ages: An immunohistochemical study 

      Dennis, CV; Suh, LS; Rodriguez, ML; Kril, JJ; Sutherland, GT
      Published 2016-01-01
      AIMS: Neurogenesis in the postnatal human brain occurs in two neurogenic niches; the subventricular zone (SVZ) in the wall of the lateral ventricles and the subgranular zone (SGZ) of the hippocampus. The extent to which ...
      Open Access
      Article
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    • Optimal Preparation of Formalin Fixed Samples for Peptide Based Matrix Assisted Laser Desorption/Ionization Mass Spectrometry Imaging Workflows. 

      O'Rourke, MB; Padula, MP; Smith, C; Youssef, P; Cordwell, S; Witting, P; Sutherland, GT; Crossett, B
      Published 2018-01-01
      The use of matrix-assisted laser desorption/ionization, mass spectrometry imaging (MALDI MSI) has rapidly expanded, since this technique analyzes a host of biomolecules from drugs and lipids to N-glycans. Although various ...
      Open Access
      Article
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