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School of Medical Sciences: Recent submissions

    • Acute alcohol co-ingestion and hospital-treated deliberate self-poisoning; is there an effect on subsequent self-harm? 

      Borusso, LD; Buckley, Nicholas A.; Kirby, KA; Carter, G; Pilgrim, JL; Chitty, Kate M.
      Published 2018-03-01
      The aim of this study was to determine the relationship between alcohol co-ingestion in an index deliberate self-poisoning (DSP) episode with repeated DSP and subsequent suicide. A retrospective cohort study was conducted ...
      Open Access
      Article
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    • Evidence supporting oxidative stress in a moderately affected area of the brain in Alzheimer’s disease 

      Youssef, P; Chami, B; Lim, J; Middleton, T; Sutherland, GT; Witting, PK
      Published 2018-08-01
      The pathogenesis of Alzheimer's disease (AD) remains to be elucidated. Oxidative damage and excessive beta-amyloid oligomers are components of disease progression but it is unclear how these factors are temporally related. ...
      Open Access
      Article
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    • Co-ingested alcohol and the timing of deliberate self-poisonings 

      Chitty, Kate M.; Kirby, Katharine; Osborne, Nicholas J.; Isbister, Geoffrey K.; Buckley, Nicholas A.
      Published 2018-08-01
      Objective: Investigating diurnal variation in the timing of suicidal behaviours offers opportunity to better understand its various proximal risk factors. Acute use of alcohol is a potent proximal risk factor for suicidal ...
      Open Access
      Article
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    • Re-investigating the effects of chronic smoking on the pathology of alcohol-related human brain damage 

      McCorkindale, AN; Sizemova, A; Sheedy, D; Kril, JJ; Sutherland, GT
      Published 2018-07-01
      Both pathological and neuroimaging studies have shown that chronic alcohol abuse causes generalized white matter, but limited gray matter, volume loss. Recent neuroimaging studies suggest that tobacco smoking also causes ...
      Open Access
      Article
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    • Identification of an immune modulation locus utilising a bovine mammary gland infection challenge model 

      Littlejohn, MD; Turner, SA; Walker, CG; Berry, SD; Tiplady, K; Sherlock, RG; Sutherland, GT; Swift, S; Garrick, D; Lacy-Hulbert, SJ; McDougall, S; Spelman, RJ; Snell, RG; Hillerton, JE
      Published 2018-01-01
      Inflammation of the mammary gland following bacterial infection, commonly known as mastitis, affects all mammalian species. Although the aetiology and epidemiology of mastitis in the dairy cow are well described, the genetic ...
      Open Access
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