School of Medical Sciences: Recent submissions

    • Understanding STEM academics' responses and resilience to educational reform of academic roles in higher education 

      Ross, Pauline Mary; Scanes, E.; Poronnik, P.; Coates, H.; Locke, W.
      Published 2022
      Background: Across the globe, there have been significant reforms to improve STEM education at all levels. A significant part of this has been teacher reform. While the responses and resilience of STEM teachers to educational ...
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    • Total infectome characterization of respiratory infections in pre-COVID-19 Wuhan, China 

      Shi, Mang; Zhao, Su; Yu, Bin; Wu, Wei-Chen; Hu, Yi; Tian, Jun-Hua; Yin, Wen; Ni, Fang; Hu, Hong-Ling; Geng, Shuang; Tan, Li; Peng, Ying; Song, Zhi-Gang; Wang, Wen; Chen, Yan-Mei; Holmes, Edward C.; Zhang, Yong-Zhen
      Published 2022
      At the end of 2019 Wuhan witnessed an outbreak of "atypical pneumonia" that later developed into a global pandemic. Metagenomic sequencing rapidly revealed the causative agent of this outbreak to be a novel coronavirus ...
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    • Co-infecting pathogens can contribute to inflammatory responses and severe symptoms in COVID-19 

      Chen, Liping; Shen, Lihan; Wu, Weichen; Guan, Wenda; Zhou, Jinchao; Luo, Gengyan; Chen, Qimin; Zhou, Hongxia; Deng, Zhenxuan; Chen, Yaoqing; Zhao, Wenjing; Jin, Wenxiang; Qiu, Minshan; Zheng, Qianwei; Wang, Yutao; Liu, Chen; Bai, Xiangxiang; Guo, Deyin; Holmes, Edward C.; Zhong, Nanshan; Shi, Mang; Yang, Zifeng
      Published 2022
      Background: The current COVID-19 pandemic is posing a major challenge to public health on a global scale. While it is generally believed that severe COVID-19 results from over-expression of inflammatory mediators (i.e., a ...
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    • Assessment of Coronavirus Disease 2019 Intervention Strategies in the Nordic Countries Using Genomic Epidemiology 

      Duchene, Sebastian; Featherstone, Leo; Freiesleben de Blasio, Birgitte; Holmes, Edward C.; Bohlin, Jon; Pettersson, John H O
      Published 2022
      We explored how the duration, size, and number of virus transmission clusters, defined as country-specific monophyletic groups in a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) phylogenetic tree, differed ...
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    • Co-infection with SARS-COV-2 Omicron and Delta Variants Revealed by Genomic Surveillance 

      Rockett, Rebecca J; Draper, Jenny; Gall, Mailie; Sim, Eby M; Arnott, Alicia; Agius, Jessica E; Johnson-Mackinnon, Jessica; Martinez, Elena; Drew, Alexander P; Lee, Clement; Ngo, Christine; Ramsperger, Marc; Ginn, Andrew N; Wang, Qinning; Fennell, Michael; Ko, Danny; Huston, Linda; Kairaitis, Lukas; Holmes, Edward C.; O'Sullivan, Matthew N; Chen, Sharon C-A; Kok, Jen; Dwyer, Dominic E; Sintchenko, Vitali
      Published 2022
      We identified the co-infection of the SARS-CoV-2 Omicron and Delta variants in two epidemiologically unrelated patients with chronic kidney disease requiring haemodialysis. Both SARS-CoV-2 variants were co-circulating ...
      Preprint
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