• Plasticity in striatopallidal projection neurons mediates the acquisition of habitual actions 

      Shan, Qiang; Christie, MacDonald J.; Balleine, Bernard W.
      Published 2015-08-01
      In instrumental conditioning, newly acquired actions are generally goal-directed and are mediated by the relationship between the action and its consequences or outcome. With continued training, however, the performance ...
      Open Access
      Article
    • Challenges for Opioid Receptor Nomenclature 

      Cox, Brian M; Christie, Macdonald J; Devi, Lakshmi; Toll, Lawrence; Traynor, John R
      Published 2015-01-01
      Recent developments in the study of the structure and function of opioid receptors raise significant challenges for the definition of individual receptor types and the development of a nomenclature that precisely describes ...
      Open Access
      Article
    • Characterisation of Nav types endogenously expressed in human SH-SY5Y neuroblastoma cells 

      Vetter, Irina; Mozar, Christine A.; Durek, Thomas; Wingerd, Joshua S.; Alewood, Paul F.; Christie, Macdonald J.; Lewis, Richard J.
      Published 2012-06-01
      The human neuroblastoma cell line SH-SY5Y is a potentially useful model for the identification and characterisation of Na(v) modulators, but little is known about the pharmacology of their endogenously expressed Na(v)s. ...
      Open Access
      Article
    • Intrathecal α-conotoxins Vc1.1, AuIB and MII acting on distinct nicotinic receptor subtypes reverse signs of neuropathic pain 

      Napier, I.A.; Klimis, H.; Rycroft, B.K.; Jin, A.H.; Alewood, P.F.; Motin, L.; Adams, D.J.; Christie, M.J.
      Published 2012-06-01
      The large diversity of peptides from venomous creatures with high affinity for molecules involved in the development and maintenance of neuropathic pain has led to a surge in venom-derived analgesic research. Some members ...
      Open Access
      Article
    • Glycine transport inhibitors for the treatment of pain. 

      Vandenberg, Robert J.; Ryan, Renae M.; Carland, Jane E.; Imlach, Wendy L.; Christie, Macdonald J.
      Published 2014-08-01
      Opioids, local anesthetics, anticonvulsant drugs, antidepressants, and non-steroidal anti-inflammatory drugs (NSAIDs) are used to provide pain relief but they do not provide adequate pain relief in a large proportion of ...
      Open Access
      Article