School of Medical Sciences: Recent submissions
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Tropomyosin Regulates Cell Migration during Skin Wound Healing
Published 2015-05-01Precise orchestration of actin polymer into filaments with distinct characteristics of stability, bundling, and branching underpins cell migration. A key regulator of actin filament specialization is the tropomyosin family ...Open AccessArticle -
Lipid analogues as potential drugs for the regulation of mitochondrial cell death
Published 2014-03-28The mitochondrion plays an important role in the production of energy as ATP, the regulation of cell viability and apoptosis, and the biosynthesis of major structural and regulatory molecules, such as lipids. During ATP ...Open AccessArticle -
Effects of 8 weeks of CPAP on lipid-based oxidative markers in obstructive sleep apnea: a randomized trial
Published 2014-12-22Dyslipidaemia and increased oxidative stress have been reported in severe obstructive sleep apnea, and both may be related to the development of cardiovascular disease. We have previously shown in a randomized crossover ...Open AccessArticle -
Occupy tissue: the movement in cancer metastasis
Published 2012-09-01The critical role of migration and invasion in cancer metastasis warrants new therapeutic approaches targeting the machinery regulating cell migration and invasion. While 2-dimensional (2D) models have helped identify a ...Open AccessArticle -
Src Kinase Determines the Dynamic Exchange of the Docking Protein NEDD9 (Neural Precursor Cell Expressed Developmentally Down-regulated Gene 9) at Focal Adhesions
Published 2014-09-05Dynamic exchange of molecules between the cytoplasm and integrin-based focal adhesions provides a rapid response system for modulating cell adhesion. Increased residency time of molecules that regulate adhesion turnover ...Open AccessArticle