Comparison of two different radiofrequency ablation systems for renal artery denervation: Evaluation of short-term and long-term follow up
Field | Value | Language |
dc.contributor.author | Al Raisi, Sara | |
dc.contributor.author | Pouliopoulos, Jim | |
dc.contributor.author | Qian, Pierre | |
dc.contributor.author | King, Patricia | |
dc.contributor.author | Byth, Karen | |
dc.contributor.author | Barry, Michael A. | |
dc.contributor.author | Swinnen, John | |
dc.contributor.author | Thiagalingam, Aravinda | |
dc.contributor.author | Thomas, Stuart | |
dc.date.accessioned | 2019-06-25 | |
dc.date.available | 2019-06-25 | |
dc.date.issued | 2019-02-15 | |
dc.identifier.citation | Catheter Cardiovasc Interv. 2019;93:E105–E111. | en_AU |
dc.identifier.uri | http://hdl.handle.net/2123/20635 | |
dc.description.abstract | Objectives: To assess the clinical efficacy of renal artery denervation (RAD) in our center and to compare the efficacy of two different radiofrequency (RF) systems. Background: Several systems are available for RF renal denervation. Whether there is a difference in clinical efficacy among various systems remains unknown. Methods: Renal artery denervation was performed on 43 patients with resistant hypertension using either the single electrode Symplicity Flex (n = 20) or the multi-electrode EnligHTN system (n = 23). Median post-procedural follow-up was 32.93 months. The primary outcome was post-procedural change in office blood pressure (BP) within 1 year (short-term follow-up). Secondary outcomes were change in office BP between 1 and 4 years (long-term follow-up) and the difference in office BP reduction between the two systems at each follow-up period. Results: For the total cohort, mean baseline office BP (systolic/diastolic) was 174/94 mmHg. At follow-up, mean changes in office BP from baseline were −19.70/−11.86 mmHg (P < 0.001) and −21.90/−13.94 mmHg (P < 0.001) for short-term and long-term follow-up, respectively. The differences in office BP reduction between Symplicity and EnligHTN groups were 8.96/1.23 mmHg (P = 0.42 for systolic BP, P = 0.83 for diastolic BP) and 9.56/7.68 mmHg (P = 0.14 for systolic BP, P = 0.07 for diastolic BP) for short-term and long-term follow-up, respectively. Conclusions: In our cohort, there was a clinically significant office BP reduction after RAD, which persisted up to 4 years. No significant difference in office BP reduction between the two systems was found. | en_AU |
dc.publisher | Catheter Cardiovasc Interv | en_AU |
dc.relation | National Health and Medical Research Council (NHMRC) and National Heart Foundation of Australia (NHF) co-funded postgraduate scholarship (NHMRC Scholarship No. 1114408, NHF Scholarship No. 101107). | en_AU |
dc.title | Comparison of two different radiofrequency ablation systems for renal artery denervation: Evaluation of short-term and long-term follow up | en_AU |
dc.type | Article | en_AU |
dc.type.pubtype | Publisher's version | en_AU |
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