Show simple item record

FieldValueLanguage
dc.contributor.authorAl Raisi, Sara
dc.contributor.authorPouliopoulos, Jim
dc.contributor.authorQian, Pierre
dc.contributor.authorKing, Patricia
dc.contributor.authorByth, Karen
dc.contributor.authorBarry, Michael A.
dc.contributor.authorSwinnen, John
dc.contributor.authorThiagalingam, Aravinda
dc.contributor.authorThomas, Stuart
dc.date.accessioned2019-06-25
dc.date.available2019-06-25
dc.date.issued2019-02-15
dc.identifier.citationCatheter Cardiovasc Interv. 2019;93:E105–E111.en_AU
dc.identifier.urihttp://hdl.handle.net/2123/20635
dc.description.abstractObjectives: To assess the clinical efficacy of renal artery denervation (RAD) in our center and to compare the efficacy of two different radiofrequency (RF) systems. Background: Several systems are available for RF renal denervation. Whether there is a difference in clinical efficacy among various systems remains unknown. Methods: Renal artery denervation was performed on 43 patients with resistant hypertension using either the single electrode Symplicity Flex (n = 20) or the multi-electrode EnligHTN system (n = 23). Median post-procedural follow-up was 32.93 months. The primary outcome was post-procedural change in office blood pressure (BP) within 1 year (short-term follow-up). Secondary outcomes were change in office BP between 1 and 4 years (long-term follow-up) and the difference in office BP reduction between the two systems at each follow-up period. Results: For the total cohort, mean baseline office BP (systolic/diastolic) was 174/94 mmHg. At follow-up, mean changes in office BP from baseline were −19.70/−11.86 mmHg (P < 0.001) and −21.90/−13.94 mmHg (P < 0.001) for short-term and long-term follow-up, respectively. The differences in office BP reduction between Symplicity and EnligHTN groups were 8.96/1.23 mmHg (P = 0.42 for systolic BP, P = 0.83 for diastolic BP) and 9.56/7.68 mmHg (P = 0.14 for systolic BP, P = 0.07 for diastolic BP) for short-term and long-term follow-up, respectively. Conclusions: In our cohort, there was a clinically significant office BP reduction after RAD, which persisted up to 4 years. No significant difference in office BP reduction between the two systems was found.en_AU
dc.publisherCatheter Cardiovasc Interven_AU
dc.relationNational Health and Medical Research Council (NHMRC) and National Heart Foundation of Australia (NHF) co-funded postgraduate scholarship (NHMRC Scholarship No. 1114408, NHF Scholarship No. 101107).en_AU
dc.titleComparison of two different radiofrequency ablation systems for renal artery denervation: Evaluation of short-term and long-term follow upen_AU
dc.typeArticleen_AU
dc.type.pubtypePublisher versionen_AU


Show simple item record

Associated file/s

Associated collections

Show simple item record

There are no previous versions of the item available.