• Aryl urea substituted fatty acids: a new class of protonophoric mitochondrial uncoupler that utilises a synthetic anion transporter 

      Rawling, Tristan; MacDermott-Opeskin, Hugh; Roseblade, Ariane; Pazderka, Curtis; Clarke, Callum; Bourget, Kirsi; Wu, Xin; Lewis, William; Noble, Benjamin; Gale, Philip A.; O'Mara, Megan L.; Cranfield, Charles; Murray, Michael
      Published 2020
      Respiring mitochondria establish a proton gradient across the mitochondrial inner membrane (MIM) that is used to generate ATP. Protein-independent mitochondrial uncouplers collapse the proton gradient and disrupt ATP ...
      Open Access
      Article
    • Advances in fluorescent and colorimetric sensors for anionic species 

      McNaughton, Daniel A.; Fares, Mohamed; Picci, Giacomo; Gale, Philip A.; Caltagirone, Claudia
      Published 2021
      In this review we cover recent developments in fluorescent and colorimetric anion sensors. These systems employ a range of different non-covalent interactions including hydrogen- and halogen-bonding, Lewis acidic boron-based ...
      Open Access
      Preprint
    • Anion binding in metal-organic frameworks 

      Wu, Xin; Gale, Philip A.
      Published 2021
      Despite commonly being used as the host for gases, solvents and other neutral molecules, metal-organic frameworks (MOFs) have received recent attention as supramolecular anion binding hosts with a broad range of environmental ...
      Open Access
      Preprint
    • Advances in applied supramolecular technologies 

      Williams, George T.; Haynes, Cally J.E.; Fares, Mohamed; Caltagirone, Claudia; Hiscock, Jennifer; Gale, Philip A.
      Published 2021
      Supramolecular chemistry is a comparatively young field that to date has mainly been focused on building a foundation of fundamental understanding. With much progress in this area, researchers are seeking to apply this ...
      Open Access
      Article
    • Order-disorder transitions of cytoplasmic N-termini in the mechanisms of P-type ATPases 

      Hossain, Khondker Rufaka; Clayton, Daniel; Goodchild, Sophia C; Rodger, Alison; Payne, Richard James; Cornelius, Flemming; Ronald, James Clarke
      Published 2020-01-01
      Membrane protein structure and function are modulated via interactions with their lipid environment. This is particularly true for the integral membrane pumps, the P-type ATPases. These ATPases play vital roles in cell ...
      Article