• Photomodulation of Transmembrane Transport and Potential by Stiff-Stilbene Based Bis(thio)ureas 

      Wezenberg, Sander J.; Chen, Li-Jun; Howe, Ethan N.W.; Wu, Xin; Siegler, Maxime A.; Gale, Philip A.; Bos, Jasper E.; Feringa, Ben L.
      Published 2021
      Membrane transport proteins fulfil important regulatory functions in biology with a common trait being their ability to respond to stimuli in the environment. Various small-molecule receptors, capable of mediating transmembrane ...
      Open Access
      Article
    • Carbazole-based bis-ureas and thioureas as electroneutral anion transporters 

      Wang, Patrick; Wu, Xin; Gale, Philip A.
      Published 2021
      We report a series of easily accessible carbazole-based bis-ureas and thioureas as effective anion receptors and transporters. The compounds exhibit moderate Cl− binding affinity in wet DMSO and Cl− transport capabilities ...
      Open Access
      Article
    • Delivering anion transporters to lipid bilayers in water 

      McNaughton, Daniel A.; To, Tsz Ying (Teresa); Hawkins, Bryson A.; Hibbs, David E.; Gale, Philip A.
      Published 2021
      Cyclodextrins have been employed as delivery agents for lipophilic anion transporters, which allow their incorporation into lipid bilayers without using an organic solvent or pre-incorporation.
      Open Access
      Article
    • Progress in Anion Receptor Chemistry 

      Macreadie, lauren K.; Gilchrist, Alexander M.; McNaughton, Daniel A.; Ryder, William G.; Fares, Mohamed; Gale, Philip A.
      Published 2022
      This review covers advances made in anion complexation in the years 2019 and 2020. Included here are developments in self-assembly, sensing, anion separation, transport, catalysis, and fundamental advances in anion recognition ...
      Open Access
      Article
    • Synthetic Na+/K+ exchangers promote apoptosis by disturbing cellular cation homeostasis 

      Park, Sang-Hyun; Hwang, Inhong; McNaughton, Daniel A.; Kinross, Airlie J.; Howe, Ethan N.W.; Xiong, Shenglun; Kilde, Martin Drøhse; Lynch, Vincent M.; Gale, Philip A.; Sessler, Jonathan L.; Shin, Injae; He, Qing
      Published 2021
      A number of artificial cation ionophores (or transporters) have been developed for basic research and biomedical applications. However, their mechanisms of action and the putative correlations between changes in intracellular ...
      Open Access
      Article