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Research Publications and Outputs: Recent submissions

    • The cost effectiveness of bevacizumab when added to capecitabine, with or without mitomycin-C, in first line treatment of metastatic colorectal cancer: results from the Australasian phase III MAX study 

      Carter, Hannah; Zannino, Diana; Simes, R John; Schofield, Deborah J; Howard, Kirsten; Zalcberg, John R; Price, Timothy J; Tebbutt, Niall C
      Published 2015-12-14
      Background: Based on the clinical data, bevacizumab has been approved in Australia and globally for the treatment of advanced colorectal cancer. However, limited evidence exists for its cost-effectiveness. The purpose of ...
      Open Access
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    • Is home warfarin self-management effective? Results of the Randomised Self-Management of Anticoagulation Research Trial 

      Warfarin SMART investigators; Dignan, Rebecca; Keech, Anthony; Gebski, Val; Mann, Kristy; Hughes, Clifford
      Published 2013-08-27
      Aims The Warfarin Self-Management Anticoagulation Research Trial (Warfarin SMART) was designed to determine whether patients self-managing warfarin (PSM) using the CoaguChek device and a dosing algorithm developed for the ...
      Open Access
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    • Phase II trial of temozolomide and pegylated liposomal doxorubicin in the treatment of patients with glioblastoma multiforme following concurrent radiotherapy and chemotherapy 

      Ananda, Sumitra; Nowak, Anna; Cher, Lawrence; Dowling, Anthony; Brown, Chris; Simes, John; Rosenthal, Mark A
      Published 2011-08-02
      Concurrent and post-radiotherapy temozolomide (T) significantly improves survival in patient with newly diagnosed glioblastoma multiforme. We aimed to assess the activity of the combination of T and pegylated liposomal ...
      Open Access
      Article
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    • Association of Contemporary Sensitive Troponin I Levels at Baseline and Change at 1 Year With Long-Term Coronary Events Following Myocardial Infarction or Unstable Angina : Results From the LIPID Study (Long-Term Intervention With Pravastatin in Ischaemic Disease) 

      White, Harvey D; Tonkin, Andrew; Simes, John; Mann, Kristy; Thompson, Peter; Colquhoun, David; West, Malcolm; Nestel, Paul; Sullivan, David; Keech, Anthony C; Hunt, David; Blankenberg, Stefan
      Published 2013-09-30
      Objectives This study sought to assess whether baseline and change in contemporary sensitive troponin I (TnI) levels predicts coronary heart disease (CHD) death and myocardial infarction (MI), and to determine the effects ...
      Open Access
      Article
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    • Efficacy and safety of LDL-lowering therapy among men and women: meta-analysis of individual data from 174,000 participants in 27 randomised trials 

      Cholesterol Treatment Trialists’ (CTT) Collaboration; Fulcher, Jordan; O'Connell, Rachel; Voysey, Merryn; Emberson, Jonathan; Blackwell, Lisa; Mihaylova, Borislava; Simes, John; Collins, Rory; Kirby, Adrienne; Colhoun, Helen; Braunwald, Eugene; LaRosa, John; Pedersen, TR; Tonkin, Andrew; Davis, Barry; Slright, Peter; Franzosi, Maria Grazia; Baigent, Colin; Keech, Anthony
      Published 2015-01-09
      Background Whether statin therapy is as effective in women as in men is debated, especially for primary prevention. We undertook a meta-analysis of statin trials in the Cholesterol Treatment Trialists' (CTT) Collaboration ...
      Open Access
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