Browsing by author "Hunter, David J."
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Acute low back pain is marked by variability: An internet-based pilot study
Suri, Pradeep; Rainville, James; Fitzmaurice, Garrett M; Katz, Jeffrey N.; Jamison, Robert N; Martha, Julia; Hartigan, Carol; Limke, Janet; Jouve, Cristin; Hunter, David J.Published 2011-10-05BACKGROUND: Pain variability in acute LBP has received limited study. The objectives of this pilot study were to characterize fluctuations in pain during acute LBP, to determine whether self-reported 'flares' of pain ...Open AccessPublisher version -
Association between bone marrow lesions detected by magnetic resonance imaging and knee pain in community residents in Korea
Kim, I. J.; Kim, D. H.; Jung, J. Y.; Song, Y. W.; Guermazi, Ali; Crema, M. D.; Hunter, David J.; Kim, H. A.Published 2013-05-01Objective: To describe the frequency of bonemarrowlesions (BMLs) detected bymagnetic resonance imaging (MRI), and to examine the association of BMLs with knee pain severity in community residents in Korea. Methods: ...Open AccessArticle -
The association between reduced knee joint proprioception and medial meniscal abnormalities using MRI in knee osteoarthritis: results from the Amsterdam osteoarthritis cohort.
van der Esch, Martin; Knoop, Jesper; Hunter, David J.; Klein, Jan-Paul; van der Leeden, Marike; Knol, Dirk L; Reiding, Dick; Vooreman, Ramon E; Gerritsen, Martijn; Roorda, Leo D; Lems, Willem F; Dekker, JoostPublished 2013-05-01BACKGROUND: Osteoarthritis (OA) of the knee is characterized by pain and activity limitations. In knee OA, proprioceptive accuracy is reduced and might be associated with pain and activity limitations. Although causes of ...Open AccessArticle -
Disease-modifying drugs for knee osteoarthritis: can they be cost-effective?
Losina, Elena; Daigle, Meghan E.; Reichmann, William M.; Suter, Lisa G.; Hunter, David J.; Solomon, Daniel H.; Walensky, Rochelle P.; Jordan, Joanne M.; Burbine, Sara A.; Patiel, A. Daniel; Katz, Jeffrey N.Published 2013-05-01OBJECTIVE: Disease-modifying osteoarthritis drugs (DMOADs) are under development. Our goal was to determine efficacy, toxicity, and cost thresholds under which DMOADs would be a cost-effective knee OA treatment. DESIGN: ...Open AccessArticle -
Does lumbar spinal degeneration begin with the anterior structures? A study of the observed epidemiology in a community-based population
Suri, Pradeep; Miyakoshi, Asako; Hunter, David J.; Jarvik, Jeffrey G; Rainville, James; Guermazi, Ali; Li, Ling; Katz, Jeffrey N.Published 2011-09-13Background- Prior studies that have concluded that disk degeneration uniformly precedes facet degeneration have been based on convenience samples of individuals with low back pain. We conducted a study to examine whether ...Open AccessArticle -
EFFECTS OF INTENSIVE DIET AND EXERCISE ON KNEE JOINT LOADS, INFLAMMATION, AND CLINICAL OUTCOMES AMONG OVERWEIGHT AND OBESE ADULTS WITH KNEE OSTEOARTHRITIS
Messier, Stephen P; Mihalko, Shannon L; Legault, Claudine; Miller, Gary D.; Nicklas, Barbara J.; DeVita, Paul; Beavers, Daniel P; Hunter, David J.; Lyles, Mary F.; Eckstein, Felix; Williamson, Jeff D; Carr, J. Jeffery; Guermazi, Ali; Loeser, Richard F.Published 2013-01-01Importance Knee osteoarthritis (OA), a common cause of chronic pain and disability, has biomechanical and inflammatory origins and is exacerbated by obesity. Objective To determine whether a ≥10% reduction in body weight ...Open AccessArticle -
Exercise therapy and patient education versus intra-articular saline injections in the treatment of knee osteoarthritis: an evidence-based protocol for an open-label randomised controlled trial (the DISCO trial)
Bandak, Elisabeth; Overgaard, Anders F.; Kristensen, Lars Erik; Ellegaard, Karen; Guldberg-Møller, Jørgen; Bartholdy, Cecilie; Hunter, David J.; Altman, Roy D.; Christensen, Robin; Bliddal, Henning; Henriksen, MariusPublished 2021BackgroundKnee osteoarthritis (OA) is a highly prevalent musculoskeletal condition causing pain, physical disability, and reduced quality of life. Exercise and patient education are non-pharmacological interventions for ...Article -
The Health and Structural Consequences of Acute Knee Injuries Involving Rupture of the Anterior Cruciate Ligament
Riordan, Edward A; Frobell, Richard B; Roemer, Frank W.; Hunter, David J.Published 2013-02-01Although there is an abundance of literature regarding the development of knee osteoarthritis after rupture of the anterior cruciate ligament (ACL), the mechanism underlying this link is not clear. Recent studies have ...Open AccessArticle -
Imaging Biomarker Validation and Qualification Report: 6th OARSI Workshop on Imaging in Osteoarthritis Combined with 3rd OA Biomarkers Workshop.
Hunter, David J.; Eckstein, Felix; Kraus, Virginia Byers; Lousina, Elena; Sandell, Linda; Guermazi, AliPublished 2013-07-01Summary The sixth Osteoarthritis Research Society International (OARSI) Workshop on Imaging in Osteoarthritis combined with the third osteoarthritis (OA) Biomarkers Workshop is the first to bring together the imaging and ...Open AccessArticle -
Imaging of Osteoarthritis
Guermazi, Ali; Hayashi, Daichi; Eckstein, Felix; Hunter, David J.; Duryea, Jeff; Roemer, Frank W.Published 2013-02-01Osteoarthritis (OA) is the most prevalent joint disorder in the elderly, and there is no effective treatment. Imaging is essential for evaluating the synovial joint structures (including cartilage, meniscus, subchondral ...Open AccessArticle -
Lifetime risk and age of diagnosis of symptomatic knee osteoarthritis in the US
Losina, Elena; Weinstein, Alexander M.; Reichmann, William M.; Burbine, Sara A.; Solomon, Daniel H.; Daigle, Meghan E.; Rome, Benjamin N.; Chen, Stephanie P.; Hunter, David J.; Suter, Lisa G.; Jordan, Joanne M.; Katz, Jeffrey N.Published 2013-05-01OBJECTIVE: To estimate the incidence and lifetime risk of diagnosed symptomatic knee osteoarthritis (OA) and the age at diagnosis of knee OA based on self-reports in the US population. METHODS: We estimated the incidence ...Open AccessArticle -
Long term joint consequences of sporting activity: preventing and managing osteoarthritis in the athlete
Bennell, Kim L; Hunter, David J.; Vicenzino, BillPublished 2012-07-31Sports participation is associated with an increased risk of future osteoarthritis (OA), much of which results from joint injury. No strong evidence exists that moderate sporting activity in the presence of normal joints ...Open AccessArticle -
Management of osteoarthritis of the knee
Bennell, Kim L; Hunter, David J.; Hinman, Rana SPublished 2012-07-30Osteoarthritis is a chronic disease; management should be patient centred and coordinated, with attention to modifiable risk factors and comorbidities Focus on conservative non-drug treatment, particularly exercise; for ...Open AccessArticle -
The MeTeOR Trial (Meniscal Tear in Osteoarthritis Research): Rationale and design features
Katz, Jeffrey N.; Chaisson, Christine E; Cole, Brian; Guermazi, Ali; Hunter, David J.; Jones, Morgan; Levy, Bruce A; Mandi, Lisa A; Martin, Scott; Marx, Robert G; Safran-Norton, Clare; Roemer, Frank W.; Skoniecki, Debra; Solomon, Daniel H.; Spindler, Kurt P.; Wright, John; Wright, Rick W; Losina, ElenaPublished 2012-11-01This paper presents the rationale and design features of the MeTeOR Trial (Meniscal Tear in Osteoarthritis Research; Clinical Trials.gov NCT00597012). MeTeOR is an NIH-funded seven-center prospective randomized controlled ...Open AccessArticle -
Morphological changes of the lateral meniscus in end-stage lateral compartment osteoarthritis of the knee.
Hwang, Seung Hyun; Jung, Kwang-Am; Lee, Won Jun; Yang, Ki Hyuk; Lee, Dong Won; Carter, Aaron; Hunter, David J.Published 2012-02-01OBJECTIVE: The aim of this study was to evaluate the morphological changes of the lateral meniscus in end-stage lateral compartment osteoarthritis (OA) of the knee. METHODS: One hundred fifty-eight knee joints from 133 ...Open AccessArticle -
Novel genetic variants associated with lumbar disc degeneration in northern Europeans: a meta-analysis of 4600 subjects.
Williams, Frances M K; Bansal, Aruna T; van Meurs, Joyce B; Bell, Jordana T; Meulenbelt, Ingrid; Suri, Pradeep; Rivadeneira, Fernando; Sambrook, Philip N; Hofman, Albert; Bierm-Zeinstra, Sita; Menni, Cristina; Kloppenburg, Megreet; Slagboom, P Eline; Hunter, David J.; MacGregor, Alex J; Uitterlinden, Andre G.; Spector, Tim DPublished 2013-07-01OBJECTIVE: Lumbar disc degeneration (LDD) is an important cause of low back pain, which is a common and costly problem. LDD is characterised by disc space narrowing and osteophyte growth at the circumference of the disc. ...Open AccessArticle -
Osteoarthritis Preface
Hunter, David J.Published 2013-02-01Osteoarthritis (OA) is the leading cause of disability among older adults. It is an incredibly prevalent condition affecting upward of 1 in 8 adults. Societal trends in aging, obesity, and increasing joint injury will lead ...Open AccessArticle -
Osteoarthritis: What does imaging tell us about its etiology.
Johnson, Victoria L; Giuffre, Bruno M; Hunter, David J.Published 2012-11-01Osteoarthritis (OA) is the most common joint disorder and a leading cause of disability. Due to an aging population and increasing obesity, the incidence of OA is rising. The etiology of OA is multifactorial and complex; ...Open AccessArticle -
Pattern of joint damage in persons with knee osteoarthritis and concomitant ACL tears.
Stein, Verena; Li, Ling; Guermazi, Ali; Zhang, Yuqing; Kwoh, C. Kent; Eaton, Charles B; Hunter, David J.Published 2012-02-01OBJECTIVE: The aim of this study was to evaluate the morphological changes of the lateral meniscus in end-stage lateral compartment osteoarthritis (OA) of the knee. METHODS: One hundred fifty-eight knee joints from 133 ...Open AccessArticle -
Presence and Extent of Severe Facet Joint Osteoarthritis Are Associated with Back Pain in Older Adults
Suri, Pradeep; Hunter, David J.; Rainville, James; Guermazi, Ali; Katz, Jeffrey N.Published 2013-09-01Objective To determine whether the presence and extent of severe lumbar facet joint osteoarthritis (OA) are associated with back pain in older adults, accounting for disc height narrowing and other covariates. Design ...Open AccessArticle
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