Sydney Digital Theses (University of Sydney Access only): Recent submissions
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Deciphering the Nanomechanical and Biochemical Signatures of Pancreatic Cancer
Published 2024Mechanical forces are ubiquitous within the human body and play vital roles in physiology and disease. Understanding the mechanisms through which these forces drive cell behaviour can provide insights into the pathogenesis ...Thesis -
Colchicine Promotes Atherosclerotic Plaque Stability via the Notch3-dependent Modulation of Smooth Muscle Cell Phenotype
Published 2024Atherosclerosis, a chronic inflammatory disease, leads to severe cardiovascular events such as myocardial infarctions and strokes, primarily due to unstable plaque rupture. Smooth muscle cell (SMC) phenotypes are critical ...Thesis -
Bimetallic Catalysts for CO2 Conversion
Published 2024CO2 hydrogenation to C1 chemicals has attracted significant interest due to concerns about global warming and the need to reduce the concentration of CO2 in the atmosphere. Converting the CO2 to a useful product is ...Thesis -
Melaleuca quinquenervia; a model for investigating the genetic basis of resistance to Austropuccinia psidii
Published 2024Austropuccinia psidii is a biotrophic fungal pathogen known to infect species within the family Myrtaceae. Originating in South America, it was first detected in the state of New South Wales in Australia in 2010. By 2022, ...Thesis -
Cubane as a 3D scaffold for fragment library construction
Published 2025A recent initiative in the pharmaceutical sciences to examine the utility of alternative core scaffolds has been driven by the need to diverge from planar, aromatic structures that have historically constituted a biased ...Thesis