• A study of novel inflammatory-based prognostic biomarkers in colorectal cancer 

  Chan, Joseph Chung Yan

  Colorectal cancer (CRC) is one the leading causes of cancer death worldwide. However, advances in cancer care are needed to optimise limited resources. Recently, novel strategies to identify accessible and inexpensive ...

• Novel anti-fibrotic agents in acute and chronic kidney disease 

  Wong, May Yue Wai

  The thesis spans the spectrum of causative and therapeutic aspects of chronic kidney disease (CKD), which is a significant and growing health burden. While it is desirable that these findings will translate into effective ...

• Heme as a determinant of brain development 

  Ozsoy, Sukran

  Metabolic support was long considered to be the only developmental function of haematopoiesis. In this role, erythroblast are considered simple carriers that transfer and deliver heme-bound diatomic oxygen to various ...

• Molecular Pathways in Low-Grade Serous Ovarian Cancer 

  Moujaber, Tania

  Low-grade serous cancer (LGSC) is a distinct subtype of ovarian cancer (OC), characterised by younger age at diagnosis and low chemotherapy response rates compared with the most common subtype, high-grade serous. Most women ...

• A role for oxidative stress in the early pathogenesis of Alzheimer’s disease 

  Youssef, Priscilla

  Background: Increased life expectancy over the decades has led to rising cases of Alzheimer’s disease (AD), claiming the lives of millions worldwide. Hallmarks of AD include plaques, tangles, and neuronal loss. Whilst ...

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