Browsing School of Psychology by subject "170101"
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Addenbrooke’s Cognitive Examination III: Psychometric Characteristics and Relations to Functional Ability in Dementia
Published 2018-09-07Objectives: The Addenbrooke’s Cognitive Examination (ACE) is a common cognitive screening test for dementia. Here, we examined the relationship between the most recent version (ACE-III) and its predecessor (ACE-R), determined ...Article -
Age-related changes in the temporal focus and self-referential content of spontaneous cognition during periods of low cognitive demand
Published 2019-09-18An intriguing aspect of human cognition is the unique capacity to mentally retreat from our immediate surroundings to consider perspectives distinct from the here and now. Despite increasing interest in this phenomenon, ...Article -
"All is not lost” - Rethinking the nature of memory and the self in dementia
Published 2019-09-18Memory and the self have long been considered intertwined, leading to the assumption that without memory, there can be no self. This line of reasoning has led to the misconception that a loss of memory in dementia necessarily ...Article -
Association between precuneus volume and autobiographical memory impairment in posterior cortical atrophy: Beyond the visual syndrome
Published 2018-03-10Posterior cortical atrophy is a neurodegenerative syndrome characterised by progressive disruption of visual and perceptual processing, associated with atrophy in the parieto-occipital cortex. Current diagnostic criteria ...Article -
Cerebellar Atrophy and Its Contribution to Cognition in Frontotemporal Dementias
Published 2018-06-07Objective: Increasing evidence suggests that cerebellar damage impacts on cognitive functions. Frontotemporal dementias (FTDs) are neurodegenerative brain conditions, primarily affecting the frontal and/or temporal lobe. ...Article -
The cerebellum in frontotemporal dementia: a meta-analysis of neuroimaging studies
Published 2019-08-19Frontotemporal dementia (FTD) is a neurodegenerative brain disorder primarily affecting the frontal and/or temporal lobes. Three main subtypes have been recognized: behavioural-variant FTD (bvFTD), semantic dementia (SD) ...Article -
Conditioned inhibition and reinforcement rate
Published 2014-01-01We investigated conditioned inhibition in a magazine approach paradigm. Rats were trained on a feature negative discrimination between an auditory conditioned stimulus (CS) reinforced at one rate versus a compound of that ...Article -
Exploring the contribution of visual imagery to scene construction – evidence from Posterior Cortical Atrophy
Published 2018-09-01Posterior Cortical Atrophy (PCA) is a rare neurodegenerative syndrome characterised by profound visuoperceptual processing disturbances, attributable to focal parieto-occipital cortical atrophy. Despite relative sparing ...Article -
External details revisited – A new taxonomy for coding ‘non-episodic’ content during autobiographical memory retrieval
Published 2018-04-24Autobiographical memory is typically held to comprise episodic and semantic elements, with the vast majority of studies to date focusing on profiles of episodic details in health and disease. In this context, ‘non-episodic’ ...Article -
Fronto-parietal contributions to episodic retrieval – evidence from neurodegenerative disorders
Published 2019-06-01Converging evidence suggests a critical role for the parietal cortices in episodic memory retrieval. Here, we examined episodic memory performance in Corticobasal Syndrome (CBS), a rare neurodegenerative disorder presenting ...Article -
The function of prospection - variations in health and disease
Published 2018-11-27Much of human life revolves around anticipating and planning for the future. It has become increasingly clear that this capacity for prospective cognition is a core adaptive function of the mind. Here, we review the role ...Article -
Hippocampal atrophy and intrinsic brain network alterations relate to impaired capacity for mind wandering in neurodegeneration
Published 2019-09-18Mind wandering represents the human capacity for internally focussed thought, and relies upon dynamic interactions between default and frontoparietal networks. The majority of studies in the field have characterised mind ...Article -
Neurocognitive mechanisms of theory of mind impairment in neurodegeneration: a transdiagnostic approach
Published 2019-02-20Much of human interaction is predicated upon our innate capacity to infer the thoughts, beliefs, emotions, and perspectives of others, in short, to possess a “theory of mind” (ToM). While the term has evolved considerably ...Article -
The other side of the coin – Semantic dementia as a lesion model for understanding recollection and familiarity
Published 2019-09-18The syndrome of semantic dementia represents the “other side of the coin” to Alzheimer’s disease, offering convergent evidence to help refine Bastin et al.’s Integrative Memory Model. By considering the Integrative Memory ...Article, Letter -
Rethinking the role of the angular gyrus in remembering the past and imagining the future - the Contextual Integration Model
Published 2017-10-18Despite consistent activation on tasks of episodic memory, the precise contribution of the left angular gyrus (AG) to mnemonic functions remains vigorously debated. Mounting evidence suggests that AG activity scales with ...Article -
Supporting data: Validation of a Bayesian adaptive estimation technique in the stop-signal task
Published 2016-11-11The Stop Signal Task (SST), a commonly used measure of response inhibition, uses standard psychophysical methods to gain an estimate of the time needed to withhold a prepotent response. Under some circumstances, conventional ...Dataset -
"Truth be told” – Semantic memory as the scaffold for veridical communication
Published 2018-01-22Theoretical accounts placing episodic memory as central to constructive and communicative functions neglect the role of semantic memory. We argue that the decontextualized nature of semantic schemas largely supersedes the ...Article, Letter -
Visuospatial dysfunction in Alzheimer’s disease and behavioural variant frontotemporal dementia
Published 2019-09-18OBJECTIVES: Approximately 30% of Alzheimer’s disease (AD) patients are misdiagnosed due to overlapping and evolving clinical features. In particular, the distinction of AD from behavioural variant frontotemporal dementia ...Article