Research Publications and Outputs: Recent submissions
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A sensitive and specific β-alanyl aminopeptidase-activated fluorogenic probe for the detection of Pseudomonas aeruginosa
Published 2016-04-13We report the synthesis of the sensitive and specific fluorogenic self-immolative substrate 8b, which is hydrolzyed by β-alanyl aminopeptidase (BAP), resulting in a 1,6-elimination and the release of the highly fluorescent ...Open AccessArticle -
Experimental and Theoretical Charge Density Distribution in Pigment Yellow 101
Published 2015-01-08The charge density distribution in 2,2'-Dihydroxy-1,1'-naphthalazine (Pigment Yellow 101; P.Y.101) has been determined using high-resolution X-ray diffraction and multipole refinement, along with density functional theory ...Open AccessPreprint -
The status of platinum anticancer drugs in the clinic and in clinical trials
Published 2010-01-01Since its approval in 1979 cisplatin has become an important component in chemotherapy regimes for the treatment of ovarian, testicular, lung and bladder cancers, as well as lymphomas, myelomas and melanoma. Unfortunately ...Open AccessArticle -
Novel platinum(II)-based anticancer complexes and molecular hosts as their drug delivery vehicles
Published 2007-01-01Open AccessArticle -
A chemical preformulation study of a host–guest complex of cucurbit[7]uril and a multinuclear platinum agent for enhanced anticancer drug delivery
Published 2009-01-01Single crystal and powder X-ray diffraction have been used to examine the host–guest complex of cucurbit[7]uril (CB[7]) and the model dinuclear platinum anticancer complex trans-[{PtCl(NH3)2}2μ-dpzm]2+ (di-Pt, dpzm= ...Open AccessArticle