School of Medical Sciences: Recent submissions
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Treatments for Latrodectism-A Systematic Review on Their Clinical Effectiveness
Published 2017-04-21Latrodectism or envenomation by widow-spiders is common and clinically significant worldwide. Alpha-latrotoxin is the mammalian-specific toxin in the venom that results in toxic effects observed in humans. Symptoms may be ...Open AccessArticle -
Nephrotoxicity-induced proteinuria increases biomarker diagnostic thresholds in acute kidney injury.
Published 2017-04-03BACKGROUND: Paraquat ingestion is frequently fatal. While biomarkers of kidney damage increase during paraquat-induced acute kidney injury (AKI), significant concurrent proteinuria may alter diagnostic thresholds for ...Open AccessArticle -
Diagnosis-based and external cause-based criteria to identify adverse drug reactions in hospital ICD-coded data: application to an Australia population-based study
Published 2017-04-27OBJECTIVES: External cause International Classification of Diseases (ICD) codes are commonly used to ascertain adverse drug reactions (ADRs) related to hospitalisation. We quantified ascertainment of ADR-related hospitalisation ...Open AccessArticle -
A randomized controlled trial of fresh frozen plasma for coagulopathy in Russell's viper (Daboia russelii) envenoming
Published 2017-02-16Essentials Russell's viper envenoming is a major health issue in South Asia and causes coagulopathy. We studied the effect of fresh frozen plasma and two antivenom doses on correcting coagulopathy. Fresh frozen plasma did ...Open AccessArticle -
Mechanisms underlying early rapid increases in creatinine in paraquat poisoning
Published 2015-03-27Background Acute kidney injury (AKI) is common after severe paraquat poisoning and usually heralds a fatal outcome. The rapid large increases in serum creatinine (Cr) exceed that which can be explained by creatinine kinetics ...Open AccessArticle