Transforming Obesity Prevention for CHILDren (TOPCHILD) Collaboration: protocol for a systematic review with individual participant data meta-analysis of behavioural interventions for the prevention of early childhood obesity
Access status:
Open Access
Type
PreprintAuthor/s
Hunter, Kylie EJohnson, Brittany J
Askie, Lisa
Golley, Rebecca K
Baur, Louise A
Marschner, Ian C
Taylor, Rachael W
Wolfenden, Luke
Wood, Charles T
Mihrshahi, Seema
Hayes, Alison J
Rissel, Chris
Robledo, Kristy P
O'Connor, Denise A
Espinoza, David
Staub, Lukas P
Chadwick, Paul
Taki, Sarah
Barba, Angie
Libesman, Sol
Aberoumand, Mason
Smith, Wendy A
Sue-See, Michelle
Hesketh, Kylie D
Thomson, Jessica L
Bryant, Maria
Paul, Ian M
Verbestel, Vera
Odar Stough, Cathleen
Wen, Li Ming
Larsen, Junilla K
O'Reilly, Sharleen L
Wasser, Heather M
Savage, Jennifer S
Ong, Ken K
Salvy, Sarah-Jeanne
Messito, Mary Jo
Gross, Rachel S
Karssen, Levie T
Rasmussen, Finn E
Campbell, Karen
Linares, Ana Maria
Øverby, Nina Cecilie
Palacios, Cristina
Joshipura, Kaumudi J
González Acero, Carolina
Lakshman, Rajalakshmi
Thompson, Amanda L
Maffeis, Claudio
Oken, Emily
Ghaderi, Ata
Campos Rivera, Maribel
Perez-Exposito, Ana B
Banna, Jinan C
de la Haye, Kayla
Goran, Michael
Røed, Margrethe
Anzman-Frasca, Stephanie
Seidler, Anna Lene
Abstract
Introduction Behavioural interventions in early life appear to show some effect in reducing childhood overweight and obesity. However, uncertainty remains regarding their overall effectiveness, and whether effectiveness differs among key subgroups. These evidence gaps have prompted ...
See moreIntroduction Behavioural interventions in early life appear to show some effect in reducing childhood overweight and obesity. However, uncertainty remains regarding their overall effectiveness, and whether effectiveness differs among key subgroups. These evidence gaps have prompted an increase in very early childhood obesity prevention trials worldwide. Combining the individual participant data (IPD) from these trials will enhance statistical power to determine overall effectiveness and enable examination of intervention-covariate interactions. We present a protocol for a systematic review with IPD meta-analysis to evaluate the effectiveness of obesity prevention interventions commencing antenatally or in the first year after birth, and to explore whether there are differential effects among key subgroups.
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See moreIntroduction Behavioural interventions in early life appear to show some effect in reducing childhood overweight and obesity. However, uncertainty remains regarding their overall effectiveness, and whether effectiveness differs among key subgroups. These evidence gaps have prompted an increase in very early childhood obesity prevention trials worldwide. Combining the individual participant data (IPD) from these trials will enhance statistical power to determine overall effectiveness and enable examination of intervention-covariate interactions. We present a protocol for a systematic review with IPD meta-analysis to evaluate the effectiveness of obesity prevention interventions commencing antenatally or in the first year after birth, and to explore whether there are differential effects among key subgroups.
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Date
2020Publisher
medRxivLicence
Creative Commons Attribution-NonCommercial 4.0Faculty/School
Faculty of Medicine and Health, NHMRC Clinical Trials CentreShare