Browsing Research Publications and Outputs by subject "0299 Other Physical Sciences"
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The adaptation and investigation of cone-beam CT reconstruction algorithms for horizontal rotation fixed-gantry scans of rabbits.
Published 2021Fixed-gantry radiation therapy has been proposed as a low-cost alternative to the conventional rotating-gantry radiation therapy, that may help meet the rising global treatment demand. Fixed-gantry systems require gravitational ...Open AccessArticle -
Adaptive CaRdiac cOne BEAm computed Tomography (ACROBEAT): Developing the next generation of cardiac cone beam CT imaging.
Published 2021Purpose: An important factor when considering the use of interventional cone beam computed tomography (CBCT) imaging during cardiac procedures is the trade-off between imaging dose and image quality. Accordingly, Adaptive ...Open AccessArticle -
Cardiac radioablation for atrial fibrillation: Target motion characterization and treatment delivery considerations.
Published 2021Purpose: The safe delivery of cardiac radioablation (CR) for atrial fibrillation (AF) is challenged by multi-direction target motion, cardiac rate variability, target proximity to critical structures, and the importance ...Open AccessArticle -
Close-range feature-based head motion tracking for MRI and PET-MRI
Published 2018Optical motion tracking systems are effective in measuring head motion during MRI and PET scans. However, most systems rely on tracking attached markers which can slip or move relative to the head. In this study, we aimed ...Open AccessConference paper -
Experimental characterisation of the magnetic field correction factor,k->B,for Roos chambers in a parallel MRI-linac.
Published 2022Objective. Reference dosimetry on an MRI-linac requires a chamber specific magnetic field correction factor,kB⃗.This work aims to measure the correction factor for a parallel plate chamber on a parallel MRI-linac. Approach. ...Open AccessArticle -
Extended Intraoperative Longitudinal 3-Dimensional Cone Beam Computed Tomography Imaging With a Continuous Multi-Turn Reverse Helical Scan.
Published 2022Objectives: Cone beam computed tomography (CBCT) imaging is becoming an indispensable intraoperative tool; however, the current field of view prevents visualization of long anatomical sites, limiting clinical utility. Here, ...Open AccessArticle -
First experimental evaluation of multi-target multileaf collimator tracking during volumetric modulated arc therapy for locally advanced prostate cancer.
Published 2021Purpose: Locally advanced and oligometastatic cancer patients require radiotherapy treatment to multiple independently moving targets. There is no existing commercial solution that can simultaneously track and treat multiple ...Open AccessArticle -
First experimental investigation of simultaneously tracking two independently moving targets on an MRI-linac using real-time MRI and MLC tracking
Published 2020Purpose: High quality radiotherapy is challenging in cases where multiple targets with independent motion are simultaneously treated. A real-time tumor tracking system that can simultaneously account for the motion of two ...Open AccessArticle -
The first-in-human implementation of adaptive 4D cone beam CT for lung cancer radiotherapy: 4DCBCT in less time with less dose.
Published 2021Background and purpose: We present the first implementation of Adaptive 4D cone beam CT (4DCBCT) that adapts the image hardware (gantry rotation speed and kV projections) in response to the patient's real-time respiratory ...Open AccessArticle -
Geometric uncertainty analysis of MLC tracking for lung SABR.
Published 2020Purpose: The purpose of this work was to report on the geometric uncertainty for patients treated with multi-leaf collimator (MLC) tracking for lung SABR to verify the accuracy of the system. Methods: Seventeen patients ...Open AccessArticle -
Magnetic modeling of actively shielded rotating MRI magnets in the presence of environmental steel.
Published 2021Rotating MRI systems could enable novel integrated medical devices such as MRI-Linacs, MRI-xray-angiography systems, and MRI-proton therapy systems. This work aimed to investigate the feasibility of rotating actively ...Open AccessArticle -
Measurements of human tolerance to horizontal rotation within an MRI scanner: Towards gantry-free radiation therapy.
Published 2021Introduction: Recent advances in image guidance and adaptive radiotherapy could enable gantry-free radiotherapy using patient rotation. Gantry-free radiotherapy could substantially reduce the cost of radiotherapy systems ...Open AccessArticle -
MRI-guided cardiac-induced target motion tracking for atrial fibrillation cardiac radioablation.
Published 2021Background and purpose: Atrial fibrillation (AF) cardiac radioablation (CR) challenges radiotherapy tracking: multiple small targets close to organs-at-risk undergo rapid differential cardiac contraction and respiratory ...Open AccessArticle -
Non-rigid motion detection for motion tracking of the head
Published 2019Optical motion tracking systems are effective tools for measuring head motion during MRI and PET scans in order to correct for motion. Most systems rely on the attachment of fiducial markers which can slip or become decoupled ...Open AccessConference paper -
Optimising multi-target multileaf collimator tracking using real-time dose for locally advanced prostate cancer patients.
Published 2022Objective. The accuracy of radiotherapy for patients with locally advanced cancer is compromised by independent motion of multiple targets. To date, MLC tracking approaches have used 2D geometric optimisation where the MLC ...Open AccessArticle -
An optimized feature detector for markerless motion tracking in motion-compensated neuroimaging
Published 2017Head movements during PET and MRI scans can have a detrimental effect on image quality and quantitative measurements. For both modalities, motion correction methods exist that rely on accurate characterization of head ...Open AccessConference paper -
Pre-treatment and real-time image guidance for a fixed-beam radiotherapy system.
Published 2021Purpose: A radiotherapy system with a fixed treatment beam and a rotating patient positioning system could be smaller, more robust and more cost effective compared to conventional rotating gantry systems. However, patient ...Open AccessArticle -
A real-time IGRT method using a Kalman filter framework to extract 3D positions from 2D projections.
Published 2021Purpose.To estimate 3D prostate motion in real-time during irradiation from 2D prostate positions acquired from a kV imager on a standard linear accelerator utilising a Kalman filter (KF) framework. The advantage of this ...Open AccessArticle -
Reducing 4DCBCT imaging dose and time: exploring the limits of adaptive acquisition and motion compensated reconstruction.
Published 2022This study investigates the dose and time limits of adaptive 4DCBCT acquisitions (adaptive-acquisition) compared with current conventional 4DCBCT acquisition (conventional-acquisition). We investigate adaptive-acquisitions ...Open AccessArticle -
Reducing 4DCBCT scan time and dose through motion compensated acquisition and reconstruction.
Published 2021Conventional 4DCBCT captures 1320 projections across 4 min. Adaptive 4DCBCT has been developed to reduce imaging dose and scan time. This study investigated reconstruction algorithms that best complement adaptive 4DCBCT ...Open AccessArticle