Browsing Research Publications and Outputs by publication year
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Pharmacology at the University of Sydney: a brief history
Published 1999A brief history of pharmacology at the University of Sydney marking 50 years from 1949-1999Open AccessArticle -
Tumor-infiltrating lymphocyte grade (TIL grade) is an independent predictor of sentinel lymph node status and survival in cutaneous melanoma patients
Published 2012Purpose: To determine whether density and distribution of tumor-infiltrating lymphocytes (TIL) (TIL grade) is an independent predictor of sentinel node (SLN) status and survival in patients with clinically localized primary ...Open AccessArticle -
PD-L1 expression in melanoma has prognostic significance but shows marked heterogeneity within and between patients- implications for anti-PD-1/PD-L1 clinical trials
Published 2015This study evaluated the expression of PD-L1 in immunotherapy-naive metastatic melanoma patients to determine longitudinal intrapatient concordance and correlate PD-L1 status with clinicopathologic characteristics and ...Open AccessArticle -
Adjuvant lymph-node field radiotherapy versus observation only in patients with melanoma at high risk of further lymph-node field relapse after lymphadenectomy (ANZMTG 01.02/TROG 02.01): 6-year follow-up of a phase 3, randomised controlled trial
Published 2015BACKGROUND: Adjuvant radiotherapy is recommended for patients with melanoma after lymphadenectomy. We previously showed this treatment reduced risk of repeat lymph-node field cancer in patients with a high risk of recurrence ...Open AccessArticle -
An optimized feature detector for markerless motion tracking in motion-compensated neuroimaging
Published 2017Head movements during PET and MRI scans can have a detrimental effect on image quality and quantitative measurements. For both modalities, motion correction methods exist that rely on accurate characterization of head ...Open AccessConference paper -
Antiplatelet therapy before or after 16 weeks' gestation for preventing preeclampsia: an individual participant data meta-analysis
Published 2017BACKGROUND: The optimum time for commencing antiplatelet therapy for the prevention of preeclampsia and its complications is unclear. Aggregate data meta-analyses suggest that aspirin is more effective if given prior to ...Article -
Close-range feature-based head motion tracking for MRI and PET-MRI
Published 2018Optical motion tracking systems are effective in measuring head motion during MRI and PET scans. However, most systems rely on tracking attached markers which can slip or move relative to the head. In this study, we aimed ...Open AccessConference paper -
CD103(+) Tumor-Resident CD8(+) T Cells Are Associated with Improved Survival in Immunotherapy-Naive Melanoma Patients and Expand Significantly During Anti-PD-1 Treatment
Published 2018Purpose: Therapeutic blockade of immune checkpoints has revolutionized cancer treatment. Durable responses, however, occur in less than half of those treated, and efforts to improve treatment efficacy are confounded by a ...Open AccessArticle -
Non-rigid motion detection for motion tracking of the head
Published 2019Optical motion tracking systems are effective tools for measuring head motion during MRI and PET scans in order to correct for motion. Most systems rely on the attachment of fiducial markers which can slip or become decoupled ...Open AccessConference paper -
The neuropsychological profiles of young psychosis patients with and without current cannabis use
Published 2019Introduction: Evidence suggests that patients with psychosis who have a history of cannabis use, but currently abstain, demonstrate superior cognitive performance than patients who have never used cannabis. The present ...Article -
Acceptability and feasibility of a computer-based application to help Aboriginal and Torres Strait Islander Australians describe their alcohol consumption
Published 2019We examined acceptability and feasibility of a tablet application (“App”) to record self-reported alcohol consumption among Aboriginal and Torres Strait Islander Australians. Four communities (1 urban; 3 regional/remote) ...Open AccessArticle -
A Novel Finger Illusion Reveals Reduced Weighting of Bimanual Hand Cortical Representations in People With Complex Regional Pain Syndrome
Published 2019-01-01Complex regional pain syndrome (CRPS) is associated with deficits in sensorimotor control. Herein we have used a novel finger illusion to investigate whether CRPS is associated with reduced weighting of bimanual hand ...Open AccessArticle -
Identifying risk and protective factors, including culture and identity, for methamphetamine use in Aboriginal and Torres Strait Islander communities: Relevance of the ‘communities that care’ model
Published 2020Background and Aims There is a need for more evidence to guide efforts to address harmful methamphetamine use amongst young Aboriginal and Torres Strait Islander Australians. ‘Communities that Care’ (CTC) is an evidence-based ...Open AccessArticle -
A context-specific instrument to record drinking behaviour: A pilot study on implications of identifying the context of risky drinking
Published 2020A context-specific quantity-frequency (CSQF) questionnaire has been developed to accurately measure alcohol consumption using probing questions on drinking context. The study aimed to describe the drinking context associated ...Open AccessArticle -
Understanding, comparing and learning from the four EPOCH early childhood obesity prevention interventions: A multi-methods study
Published 2020Background Childhood obesity is a global problem. Early obesity prevention interventions are complex and differ in effectiveness. Novel frameworks, taxonomies and experience from the Early Prevention of Obesity in CHildren ...Open AccessArticle -
Interventions commenced by early infancy to prevent childhood obesity - The EPOCH Collaboration: An individual participant data prospective meta-analysis of four randomized controlled trials
Published 2020Background Childhood obesity is a significant global problem. Childhood obesity prevention interventions may be more effective when started very early in life before metabolic and behavioural patterns are established. Methods ...Open AccessArticle -
Systematic Review and network meta-analysis with individual participant data on cord management at preterm birth (iCOMP): study protocol
Published 2020Introduction Timing of cord clamping and other cord management strategies may improve outcomes at preterm birth. However, it is unclear whether benefits apply to all preterm subgroups. Previous and current trials compare ...Open AccessArticle -
First experimental investigation of simultaneously tracking two independently moving targets on an MRI-linac using real-time MRI and MLC tracking
Published 2020Purpose: High quality radiotherapy is challenging in cases where multiple targets with independent motion are simultaneously treated. A real-time tumor tracking system that can simultaneously account for the motion of two ...Open AccessArticle -
Drinking risk varies within and between Australian Aboriginal and Torres Strait Islander samples: a meta-analysis to identify sources of heterogeneity
Published 2020Background and Aims To reduce health and social inequities, it is important to understand how drinking patterns vary within and between Indigenous peoples. We aimed to assess variability in estimates of Indigenous ...Open AccessArticle -
Geometric uncertainty analysis of MLC tracking for lung SABR.
Published 2020Purpose: The purpose of this work was to report on the geometric uncertainty for patients treated with multi-leaf collimator (MLC) tracking for lung SABR to verify the accuracy of the system. Methods: Seventeen patients ...Open AccessArticle