Browsing Research Publications and Outputs by publication year
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Pharmacology at the University of Sydney: a brief history
Published 1999A brief history of pharmacology at the University of Sydney marking 50 years from 1949-1999Open AccessArticle -
Tumor-infiltrating lymphocyte grade (TIL grade) is an independent predictor of sentinel lymph node status and survival in cutaneous melanoma patients
Published 2012Purpose: To determine whether density and distribution of tumor-infiltrating lymphocytes (TIL) (TIL grade) is an independent predictor of sentinel node (SLN) status and survival in patients with clinically localized primary ...Open AccessArticle -
PD-L1 expression in melanoma has prognostic significance but shows marked heterogeneity within and between patients- implications for anti-PD-1/PD-L1 clinical trials
Published 2015This study evaluated the expression of PD-L1 in immunotherapy-naive metastatic melanoma patients to determine longitudinal intrapatient concordance and correlate PD-L1 status with clinicopathologic characteristics and ...Open AccessArticle -
Adjuvant lymph-node field radiotherapy versus observation only in patients with melanoma at high risk of further lymph-node field relapse after lymphadenectomy (ANZMTG 01.02/TROG 02.01): 6-year follow-up of a phase 3, randomised controlled trial
Published 2015BACKGROUND: Adjuvant radiotherapy is recommended for patients with melanoma after lymphadenectomy. We previously showed this treatment reduced risk of repeat lymph-node field cancer in patients with a high risk of recurrence ...Open AccessArticle -
An optimized feature detector for markerless motion tracking in motion-compensated neuroimaging
Published 2017Head movements during PET and MRI scans can have a detrimental effect on image quality and quantitative measurements. For both modalities, motion correction methods exist that rely on accurate characterization of head ...Open AccessConference paper -
Cognition in Parkinson's disease
Published 2017Cognitive decline is now recognised as a common non-motor symptom of Parkinson’s disease, and it has been the subject of increasing research in recent decades. Cognitive deficits in Parkinson’s disease can be distinguished ...Open AccessArticle -
Antiplatelet therapy before or after 16 weeks' gestation for preventing preeclampsia: an individual participant data meta-analysis
Published 2017BACKGROUND: The optimum time for commencing antiplatelet therapy for the prevention of preeclampsia and its complications is unclear. Aggregate data meta-analyses suggest that aspirin is more effective if given prior to ...Article -
CD103(+) Tumor-Resident CD8(+) T Cells Are Associated with Improved Survival in Immunotherapy-Naive Melanoma Patients and Expand Significantly During Anti-PD-1 Treatment
Published 2018Purpose: Therapeutic blockade of immune checkpoints has revolutionized cancer treatment. Durable responses, however, occur in less than half of those treated, and efforts to improve treatment efficacy are confounded by a ...Open AccessArticle -
Close-range feature-based head motion tracking for MRI and PET-MRI
Published 2018Optical motion tracking systems are effective in measuring head motion during MRI and PET scans. However, most systems rely on tracking attached markers which can slip or move relative to the head. In this study, we aimed ...Open AccessConference paper -
The neuropsychological profiles of young psychosis patients with and without current cannabis use
Published 2019Introduction: Evidence suggests that patients with psychosis who have a history of cannabis use, but currently abstain, demonstrate superior cognitive performance than patients who have never used cannabis. The present ...Article -
The multifaceted nature of impulsivity in Parkinson’s disease
Published 2019This scientific commentary refers to "Mosley PE, Paliwal S, Robinson K, Coyne T, Silburn P, Tittgemeyer M, Stephan KE, Breakspear M, Perry A. The structural connectivity of discrete networks underlies impulsivity and ...Open AccessArticle -
Acceptability and feasibility of a computer-based application to help Aboriginal and Torres Strait Islander Australians describe their alcohol consumption
Published 2019We examined acceptability and feasibility of a tablet application (“App”) to record self-reported alcohol consumption among Aboriginal and Torres Strait Islander Australians. Four communities (1 urban; 3 regional/remote) ...Open AccessArticle -
Non-rigid motion detection for motion tracking of the head
Published 2019Optical motion tracking systems are effective tools for measuring head motion during MRI and PET scans in order to correct for motion. Most systems rely on the attachment of fiducial markers which can slip or become decoupled ...Open AccessConference paper -
A Novel Finger Illusion Reveals Reduced Weighting of Bimanual Hand Cortical Representations in People With Complex Regional Pain Syndrome
Published 2019-01-01Complex regional pain syndrome (CRPS) is associated with deficits in sensorimotor control. Herein we have used a novel finger illusion to investigate whether CRPS is associated with reduced weighting of bimanual hand ...Open AccessArticle -
Cancer mortality in kidney transplant recipients: An Australian and New Zealand population-based cohort study, 1980-2013
Published 2020Cancer burden is increasing in kidney transplant recipients, but differences in mortality compared to the general population remain unclear. We sought to compare cancer mortality in paediatric and adult kidney transplant ...Open AccessArticle -
A context-specific instrument to record drinking behaviour: A pilot study on implications of identifying the context of risky drinking
Published 2020A context-specific quantity-frequency (CSQF) questionnaire has been developed to accurately measure alcohol consumption using probing questions on drinking context. The study aimed to describe the drinking context associated ...Open AccessArticle -
Understanding, comparing and learning from the four EPOCH early childhood obesity prevention interventions: A multi-methods study
Published 2020Background Childhood obesity is a global problem. Early obesity prevention interventions are complex and differ in effectiveness. Novel frameworks, taxonomies and experience from the Early Prevention of Obesity in CHildren ...Open AccessArticle -
First experimental investigation of simultaneously tracking two independently moving targets on an MRI-linac using real-time MRI and MLC tracking
Published 2020Purpose: High quality radiotherapy is challenging in cases where multiple targets with independent motion are simultaneously treated. A real-time tumor tracking system that can simultaneously account for the motion of two ...Open AccessArticle -
Drinking risk varies within and between Australian Aboriginal and Torres Strait Islander samples: a meta-analysis to identify sources of heterogeneity
Published 2020Background and Aims To reduce health and social inequities, it is important to understand how drinking patterns vary within and between Indigenous peoples. We aimed to assess variability in estimates of Indigenous ...Open AccessArticle -
Towards real-time 4D radiation dosimetry on an MRI-Linac
Published 20204D radiation dosimetry using a highly radiation-sensitive polymer gel dosimeter with real-time quantitative magnetic resonance imaging (MRI) readout is presented as a technique to acquire the accumulated radiation dose ...Open AccessArticle