Total Synthesis of Polydiscamides B, C, and D via a Convergent Native Chemical Ligation–Oxidation Strategy

Santhakumar, Gajan; Payne, Richard J.

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Open Access

Field	Value	Language
dc.contributor.author	Santhakumar, Gajan
dc.contributor.author	Payne, Richard J.
dc.date.accessioned	2020-06-19
dc.date.available	2020-06-19
dc.date.issued	2014-08-08
dc.identifier.uri	https://hdl.handle.net/2123/22620
dc.description.abstract	The first total syntheses of the marine sponge-derived cyclic depsipeptide natural products Polydiscamides B, C, and D are described. The molecules were constructed through the convergent fusion of cyclic and linear fragments via an unprecedented native chemical ligation–oxidation protocol.	en
dc.language.iso	en_US	en
dc.publisher	American Chemical Society	en
dc.rights	Other	en
dc.subject	Purification	en
dc.subject	Peptides and proteins	en
dc.subject	Organic polymers	en
dc.subject	Organic synthesis	en
dc.subject	Pharmaceuticals	en
dc.title	Total Synthesis of Polydiscamides B, C, and D via a Convergent Native Chemical Ligation–Oxidation Strategy	en
dc.type	Article	en
dc.subject.asrc	FoR::030599 - Organic Chemistry not elsewhere classified	en
dc.subject.asrc	FoR::030499 - Medicinal and Biomolecular Chemistry not elsewhere classified	en
dc.subject.asrc	FoR::030502 - Natural Products Chemistry	en
dc.identifier.doi	10.1021/ol502045u
dc.type.pubtype	Author accepted manuscript	en
dc.rights.other	This document is the Accepted Manuscript version of a Published Work that appeared in final form in Organic Letters, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/ol502045u	en
usyd.faculty	SeS faculties schools::Faculty of Science	en