UniversityLibraryCurrent studentsStaff intranet
University of Sydney
University of Sydney
View Item 
  • Sydney eScholarship Home
  • Engineering and Information Technologies
  • Research Papers and Publications. Engineering and Information Technologies
  • View Item
  • Sydney eScholarship Home
  • Engineering and Information Technologies
  • Research Papers and Publications. Engineering and Information Technologies
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Comparison of new-generation renal artery denervation systems: assessing lesion size and thermodynamics using a thermochromic liquid crystal phantom model

Thumbnail
View/Open
comparison-of-new-ge.pdf (PDF, 871.25KB)
Date
2017-11-20
Author
Al Raisi, S
Barry, Michael A.
Qian, Pierre
Bhaskaran, Abhishek
Pouliopoulos, Jim
Kovoor, Pramesh
Metadata
Show full item record
Abstract
Aims: The aim of this study was to evaluate and compare lesion dimensions and thermodynamics of the new-generation multi-electrode Symplicity Spyral and the new-generation multi-electrode EnligHTN renal artery denervation systems, using a thermochromic liquid crystal phantom model. Methods and results: A previously described renal artery phantom model was used as a platform for radiofrequency ablation. A total of 32 radiofrequency ablations were performed using the multi-electrode Symplicity Spyral (n=16) and the new-generation EnligHTN systems (n=16). Both systems were used as clinically recommended by their respective manufacturer. Lesion borders were defined by the 51°C isotherm. Lesion size (depth and width) was measured and compared between the two systems. Mean lesion depth was 2.15±0.02 mm for the Symplicity Spyral and 2.32±0.02 mm for the new-generation EnligHTN (p-value <0.001). Mean lesion width was 3.64±0.08 mm and 3.59±0.05 mm (p-value=0.61) for the Symplicity Spyral and the new-generation EnligHTN, respectively. Conclusions: The new-generation EnligHTN system produced lesions of greater depth compared to the Symplicity Spyral under the same experimental conditions. Lesion width was similar between both systems. Achieving greater lesion depth by use of the new-generation EnligHTN may result in better efficacy of renal artery denervation.
URI
http://hdl.handle.net/2123/20631
Collections
  • Research Papers and Publications. Engineering and Information Technologies [154]

Browse

All of Sydney eScholarshipCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

My Account

LoginRegister

Statistics

Most Popular ItemsStatistics by CountryMost Popular Authors

Links

University homeLibraryCurrent studentsStaff intranet

Repository

  • About us
  • FAQ
  • Policies & guidelines
  • Email us
  • Non-UniKey login
Leadership for good starts here

Media

  • News
  • Find an expert
  • Media contacts

Student links

  • Log in to University systems
  • Study dates
  • Student handbooks
  • Timetables
  • Library

About us

  • Our world rankings
  • Faculties and schools
  • Centres and institutes
  • Campus locations
  • Maps and locations

Connect

  • Contact us
  • Find a staff member
  • Careers at Sydney
  • Events
  • Emergencies and personal safety
Inspired: Campaign to support the University of SydneyGroup of Eight
Disclaimer
Privacy
Accessibility
Website feedback
ABN: 15 211 513 464
CRICOS Number: 00026A
Disclaimer
Privacy
Accessibility
Website feedback
ABN: 15 211 513 464
CRICOS Number: 00026A