Nebulisation effects on structural stability of bacteriophage PEV44
Access status:
Open Access
Type
Conference paperAuthor/s
Astudillo, ArielLeung, Sharon Shui Yee
Kutter, Elizabeth
Morales, Sandra
Britton, Warwick J
Chan, Hak-Kim
Abstract
Nebulization being used for inhaled phage therapy can cause phage titer losses which may be the result of mechanical damage to the phages. This study aimed to determine effects of nebulization on the structural stability and bioactivity of a Pseudomonas lytic phage PEV44, which is a myovirus consisting of a hexagonal head and a contractile tail connected by a neck.Nebulization being used for inhaled phage therapy can cause phage titer losses which may be the result of mechanical damage to the phages. This study aimed to determine effects of nebulization on the structural stability and bioactivity of a Pseudomonas lytic phage PEV44, which is a myovirus consisting of a hexagonal head and a contractile tail connected by a neck.
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Date
2017-08-11Publisher
The Evergreen State College, Olympia, WA, USAShare