• Confinement Assembly of ABC Triblock Terpolymers for the High-Yield Synthesis of Janus Nanorings 

      Steinhaus, Andrea; Chakroun, Ramzi; Müllner, Markus; Nghiem, Tai-Lam; Hildebrandt, Marcus; Groeschel, Andre H.
      Published 2019-05-13
      Block copolymers are versatile building blocks for the self-assembly of functional nanostructures in bulk and solution. While spheres, cylinders, and bilayer sheets are thermodynamically preferred shapes and frequently ...
      Open Access
      Article
    • New Insights into the Anion Transport Selectivity and Mechanism of Tren-based Tris-(thio)ureas 

      Jowett, Laura A.; Howe, Ethan N.W.; Wu, Xin; Busschaert, Nathalie; Gale, Philip A.
      Published 2018-06-19
      The anion transport properties of a series of previously reported tren-based anionophores have been revisited using new assays designed to measure anion uniport. This study provides new insights into the transport mechanism ...
      Open Access
      Article
    • Full elucidation of the transmembrane anion transport mechanism of squaramides using in silico investigations 

      Marques, Igor; Costa, Pedro M.R.; Miranda, Margarida Q.; Busschaert, Nathalie; Howe, Ethan N.W.; Clarke, Harriet J.; Haynes, Cally J.E.; Kirby, Isabelle L.; Rodilla, Ananda M.; Pérez-Tomás, Ricardo; Gale, Philip A.; Félix, Vítor
      Published 2018-06-29
      A comprehensive experimental and theoretical investigation of the transmembrane chloride transport promoted by four series of squaramide derivatives, with different degrees of fluorination, number of convergent N–H binding ...
      Open Access
      Article
    • Real-Time Recording of the Cellular Effects of the Anion Transporter Prodigiosin 

      Cheung, Shane; Wu, Dan; Daly, Harrison C.; Busschaert, Nathalie; Morgunova, Marina; Simpson, Jeremy C.; Scholz, Dimitri; Gale, Philip A.; O'Shea, Donal F.
      Published 2018-04-12
      The unraveling of the cellular effects of anion transporters is key to their potential development as apoptosis-inducing or autophagy-disrupting therapeutics. Here, we conducted a systematic study of the cellular responses ...
      Open Access
      Preprint
    • Formation of Australian continental margin highlands driven by plate-mantle interaction 

      Muller, R. Dietmar; Flament, Nicolas; Matthews, Kara J; Williams, Simon E; Gurnis, Michael
      Published 2016-05-01
      Passive margin highlands occur on most continents on Earth and play a critical role in the cycle of weathering, erosion, and atmospheric circulation. Yet, in contrast to the well-developed understanding of collisional ...
      Article