• Investigating the Influence of Steric Hindrance on Selective Anion Transport 

      Jowett, Laura A.; Ricci, Angela; Wu, Xin; Howe, Ethan N.W.; Gale, Philip A.
      Published 2019-04-02
      A series of symmetrical and unsymmetrical alkyl tren based tris-thiourea anion transporters were synthesised and their anion binding and transport properties studied. Overall, increasing the steric bulk of the substituents ...
      Open Access
      Article
    • Promises and Pitfalls of Metal Imaging in Biology 

      New, Elizabeth J; Wimmer, Verena C; Hare, Dominic J
      Published 2017-11-16
      A picture may speak a thousand words, but if those words fail to form a coherent sentence there is little to be learned. As cutting-edge imaging technology now provides us the tools to decipher the multitude of roles played ...
      Open Access
      Preprint
    • Squaramide-based synthetic chloride transporters activate TFEB but block autophagic flux 

      Zhang, Shaoyi; Wang, Yan; Xie, Wei; Howe, Ethan N.W.; Busschaert, Nathalie; Sauvat, Allan; Leduc, Marion; Gomes-da-Silva, Ligia C.; Chen, Guo; Martins, Isabelle; Deng, Xiaxing; Maiuri, Luigi; Kepp, Oliver; Soussi, Thierry; Gale, Philip A.; Zamzami, Naoufal; Kroemer, Guido
      Published 2019-02-01
      Cystic fibrosis is a disease caused by defective function of a chloride channel coupled to a blockade of autophagic flux. It has been proposed to use synthetic chloride transporters as pharmacological agents to compensate ...
      Open Access
      Article
    • Very narrow coronal mass ejections producing solar energetic particles 

      Bronarska, K.; Wheatland, Michael S.; Gopalswamy, N.; Michalek, G.
      Published 2018-11-06
      Aims. Our main aim is to study the relationship between low-energy solar particles (energies below 1 MeV) and very narrow coronal mass ejections (“jets” with angular width ≤20 ◦ ). Methods. For this purpose, we considered ...
      Open Access
      Article
    • Leaf water stable isotopes and water transport outside the xylem 

      Barbour, MM; Farquhar, GD; Buckley, TN
      Published 2016-01-01
      Article