Discipline of Pharmacology: Recent submissions
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Role of dynamin in elongated cell migration in a 3D matrix.
Published 2015-03-01The use of 3-dimensional (3D) collagen gels has yielded new insights into the migratory behaviour of cancer cells. While the large GTPase dynamin has emerged as an important regulator of cancer cell migration and invasion ...Open AccessArticle -
Tropomyosin Regulates Cell Migration during Skin Wound Healing
Published 2015-05-01Precise orchestration of actin polymer into filaments with distinct characteristics of stability, bundling, and branching underpins cell migration. A key regulator of actin filament specialization is the tropomyosin family ...Open AccessArticle -
Lipid analogues as potential drugs for the regulation of mitochondrial cell death
Published 2014-03-28The mitochondrion plays an important role in the production of energy as ATP, the regulation of cell viability and apoptosis, and the biosynthesis of major structural and regulatory molecules, such as lipids. During ATP ...Open AccessArticle -
Effects of 8 weeks of CPAP on lipid-based oxidative markers in obstructive sleep apnea: a randomized trial
Published 2014-12-22Dyslipidaemia and increased oxidative stress have been reported in severe obstructive sleep apnea, and both may be related to the development of cardiovascular disease. We have previously shown in a randomized crossover ...Open AccessArticle -
Occupy tissue: the movement in cancer metastasis
Published 2012-09-01The critical role of migration and invasion in cancer metastasis warrants new therapeutic approaches targeting the machinery regulating cell migration and invasion. While 2-dimensional (2D) models have helped identify a ...Open AccessArticle