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  • Discipline of Pharmacology
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Discipline of Pharmacology: Recent submissions

    • Mechanisms underlying early rapid increases in creatinine in paraquat poisoning 

      Mohamed, F.; Endre, Z.; Jayamanne, S.; Pianta, T.; Peake, P.; Palangasinghe, C.; Chathuranga, U.; Jayasekera, K.; Wunnapuk, K.; Shihana, F.; Shahmy, S.; Buckley, Nicholas A.
      Published 2015-03-27
      Background Acute kidney injury (AKI) is common after severe paraquat poisoning and usually heralds a fatal outcome. The rapid large increases in serum creatinine (Cr) exceed that which can be explained by creatinine kinetics ...
      Open Access
      Article
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    • Kinetic Estimation of GFR Improves Prediction of Dialysis and Recovery after Kidney Transplantation 

      Pianta, T. J.; Endre, Z. H.; Pickering, J. W.; Buckley, Nicholas A.; Peake, P. W.
      Published 2015-05-04
      Background The early prediction of delayed graft function (DGF) would facilitate patient management after kidney transplantation. Methods In a single-centre retrospective analysis, we investigated kinetic estimated GFR ...
      Open Access
      Article
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    • Clinical and Pharmacological Investigation of Myotoxicity in Sri Lankan Russell's Viper (Daboia russelii) Envenoming 

      Silva, A.; Johnston, C.; Kuruppu, S.; Kneisz, D.; Maduwage, K.; Kleifeld, O.; Smith, A. I.; Siribaddana, S.; Buckley, Nicholas A.; Hodgson, W. C.; Isbister, G. K.
      Published 2016-12-02
      BACKGROUND: Sri Lankan Russell's viper (Daboia russelii) envenoming is reported to cause myotoxicity and neurotoxicity, which are different to the effects of envenoming by most other populations of Russell's vipers. This ...
      Open Access
      Article
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    • Dexamethasone Modifies Cystatin C-Based Diagnosis of Acute Kidney Injury During Cisplatin-Based Chemotherapy 

      Pianta, Timothy J.; Pickering, John W.; Succar, Lena; Chin, Melvin; Davidson, Trent; Buckley, Nicholas A.; Mohamed, Fahim; Endre, Zoltan H.
      Published 2017-03-17
      BACKGROUND/AIMS: Plasma cystatin C (pCysC) may be superior to serum creatinine (sCr) as a surrogate of GFR. However, the performance of pCysC for diagnosing acute kidney injury (AKI) after cisplatin-based chemotherapy is ...
      Open Access
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    • Hippocampal glutamatergic/NMDA receptor functioning in bipolar disorder: a combined MMN and 1H-MRS study 

      Chitty, Kate M.; Lagopoulos, Jim; Hickie, Ian B.; Hermens, Daniel F.
      Published 2015-08-30
      Disturbances in the hippocampal glutamate (Glu)/N-methyl-d-aspartate (NMDA) system have been implicated in the pathophysiology of bipolar disorder (BD). Here we aim to provide a targeted integration of two measures of ...
      Open Access
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