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dc.contributor.authorGraves, Nicholas
dc.contributor.authorJanda, Monica
dc.contributor.authorMerolini, Katherina
dc.contributor.authorGebski, Val
dc.contributor.authorObermair, Andreas
dc.date.accessioned2015-12-01
dc.date.available2015-12-01
dc.date.issued2013-02-25
dc.identifier.citationGraves N, Janda M, Merollini K, Gebski V, Obermair A, LACE trial committee. The cost-effectiveness of total laparoscopic hysterectomy compared to total abdominal hysterectomy for the treatment of early stage endometrial cancer. BMJ Open 2013; 3(4): e001884.en
dc.identifier.urihttp://hdl.handle.net/2123/14077
dc.description.abstractObjective: To summarise how costs and health benefits will change with the adoption of total laparoscopic hysterectomy compared to total abdominal hysterectomy for the treatment of early stage endometrial cancer. Design: Cost-effectiveness modelling using the information from a randomised controlled trial. Participants: Two hypothetical modelled cohorts of 1000 individuals undergoing total laparoscopic hysterectomy and total abdominal hysterectomy. Outcome measures: Surgery costs; hospital bed days used; total healthcare costs; quality-adjusted life years; and net monetary benefits. Results: For 1000 individuals receiving total laparoscopic hysterectomy surgery, the costs were $509 575 higher, 3548 hospital fewer bed days were used and total health services costs were reduced by $3 746 221. There were 39.13 more quality-adjusted life years for a 5 year period following surgery. Conclusions: The adoption of total laparoscopic hysterectomy is almost certainly a good decision for health services policy makers. There is 100% probability that it will be cost saving to health services, a 86.8% probability that it will increase health benefits and a 99.5% chance that it returns net monetary benefits greater than zero.en
dc.description.sponsorshipCancer Council Queensland, Cancer Council New South Wales, Cancer Council Victoria, Cancer Council Western Australia; NHMRC project grant 456110; Cancer Australia project grant 631523; the Women and Infants Research Foundation, Western Australia; Royal Brisbane and Women’s Hospital Foundation; Wesley Research Institute; Gallipoli Research Foundation; Gynetech; TYCO Healthcare, Australia; Johnson and Johnson Medical, Australia; Hunter New England Centre for Gynaecological Cancer; Genesis Oncology Trust; and Smart Health Research Grant/QLD Health. MJ is supported by a National Health and Medical Research Council Career Development Award 1045247. The investigators also acknowledge the support of the Australian Gynaecological Endoscopy Society (AGES) to specifically conduct the cost-effectiveness analysis.en
dc.language.isoenen
dc.publisherBMJen
dc.rightsOther
dc.subjectendometrial canceren
dc.subjecthysterectomyen
dc.subjecteconomic studyen
dc.subjecthealth servicesen
dc.subjectcost-effectivenessen
dc.titleThe cost-effectiveness of total laparoscopic hysterectomy compared to total abdominal hysterectomy for the treatment of early stage endometrial canceren
dc.typeArticleen
dc.identifier.doi10.1136/bmjopen-2012-001884
dc.type.pubtypePublisher's versionen
usyd.facultyFaculty of Medicine and Health, NHMRC Clinical Trials Centreen


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