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Research Publications and Outputs: Recent submissions

    • Opposite associations between alanine aminotransferase and γ-glutamyl transferase levels and all-cause mortality in type 2 diabetes: analysis of the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study 

      Williams, Kathryn H; Sullivan, David R; Nicholson, Geoffrey C; George, Jacob; Jenkins, Alicia J; Januszewski, Andrzej S; Gebski, Val J; Manning, Patrick; Tan, Yong Mong; Donoghoe, Mark W; Ehnholm, Christian; Young, Simon; O'Brien, Richard; Buizen, Luke; Twigg, Stephen M; Keech, Anthony C
      Published 2016-04-18
      Aims Reported associations between liver enzymes and mortality may not hold true in type 2 diabetes, owing to a high prevalence of non-alcoholic fatty liver disease, which has been linked to cardiovascular disease and ...
      Open Access
      Article
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    • Low alanine aminotransferase levels and higher number of cardiovascular events in people with type 2 diabetes: analysis of the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study 

      Williams, KH; Sullivan, DR; Veillard, AS; O'Brien, R; George, J; Jenkins, AJ; Young, S; Ehnholm, C; Duffield, A; Twigg, SM; Keech, AC
      Published 2015-10-04
      Aims Non-alcoholic fatty liver disease (NAFLD) is common in type 2 diabetes and associated with higher risk of cardiovascular disease. This study aimed to determine whether alanine aminotransferase (ALT) or gamma-glutamy ...
      Open Access
      Article
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    • Inappropriate sinus tachycardia: focus on ivabradine 

      Abed, Hany S; Fulcher, Jordan; Kilborn, Michael J; Keech, Anthony C
      Published 2016-04-10
      Inappropriate sinus tachycardia (IST) is an incompletely understood condition characterised by an elevation in heart rate (HR) accompanied by wide ranging symptoms, in the absence of an underlying physiological stimulus. ...
      Open Access
      Article
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    • Validating self-report and proxy reports of the Dexamethasone Symptom Questionnaire-Chronic for the evaluation of longer-term corticosteroid toxicity 

      Agar, Meera; Koh, E.S.; Gibbs, Emma; Barnes, Elizabeth H.; Hovey, Elizabeth; Livingstone, Ann; Sawkins, Kate; Chye, R; Lovell, M.R.; Clark, K.; Vardy, J.; King, Madeleine
      Published 2015-08-21
      PURPOSE: In brain tumours, brain metastases or advanced cancer; treatment with corticosteroids, side effects can add to symptoms. These are best assessed by patients, complementing clinical assessment. We assessed the ...
      Open Access
      Article
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    • Linking the evidence: intermediate outcomes in medical test assessments 

      Staub, Lukas P; Dyer, Suzanne; Lord, Sarah J; Simes, R John
      Published 2012-01-01
      Objectives To review how health technology assessments (HTA) of medical tests incorporate intermediate outcomes in conclusions about the effectiveness of tests on improving health outcomes. Methods Systematic review of ...
      Open Access
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