• Estimation of adjusted rate differences using additive negative binomial regression 

      Donoghoe, Mark W; Marschner, Ian C
      Published 2016-04-14
      Rate differences are an important effect measure in biostatistics and provide an alternative perspective to rate ratios. When the data are event counts observed during an exposure period, adjusted rate differences may be ...
      Open Access
      Article
    • Hope, optimism and survival in a randomized trial of chemotherapy for metastatic colorectal cancer 

      Schofield, PE; Stockler, MR; Zannino, D; Tebbutt, NC; Price, TJ; Simes, R John; Wong, N; Pavlakis, N; Ransom, D; Moylan, E; Underhill, C; Wyld, D; Burns, i; Ward, R; Wilcken, N; Jefford, M
      Published 2015-06-21
      Purpose: Psychological responses to cancer are widely believed to affect survival. We investigated associations between hope, optimism, anxiety, depression, health utility and survival in patients starting first line ...
      Open Access
      Article
    • Inappropriate sinus tachycardia: focus on ivabradine 

      Abed, Hany S; Fulcher, Jordan; Kilborn, Michael J; Keech, Anthony C
      Published 2016-04-10
      Inappropriate sinus tachycardia (IST) is an incompletely understood condition characterised by an elevation in heart rate (HR) accompanied by wide ranging symptoms, in the absence of an underlying physiological stimulus. ...
      Open Access
      Article
    • QT interval, corrected for heart rate, is associated with HbA concentration and autonomic function in diabetes 

      Stern, K; Cho, Y.H.; Benitez-Aguirre, P; Jenkins, Alicia J.; McGill, M; Mitchell, Paul; Keech, Anthony C; Donaghue, Kim C
      Published 2016-01-30
      Aims To examine QT intervals corrected for heart rate (QTc) in adolescents with Type 1 diabetes compared with control subjects, and to determine associations with metabolic control and autonomic function. Methods Resting ...
      Open Access
      Article
    • Linking the evidence: intermediate outcomes in medical test assessments 

      Staub, Lukas P; Dyer, Suzanne; Lord, Sarah J; Simes, R John
      Published 2012-01-01
      Objectives To review how health technology assessments (HTA) of medical tests incorporate intermediate outcomes in conclusions about the effectiveness of tests on improving health outcomes. Methods Systematic review of ...
      Open Access
      Post-print